Mike J R Kent

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OBJECTIVE To design and implement the Lovelace Diabetes EPISODES OF CARE program in a managed care setting. This program is intended to address the complex needs of patients with type 2 diabetes mellitus by using specific physician-provider and patient interventions. DESIGN Observational study. SETTING Lovelace Health Systems, the second-largest and(More)
E&acts of pineapple stem tissue constitute the most potent known source of indoleacetic acid oxidase, despite the presence of an inhibitor which is difficult to remove without simultaneously removing some other factor necessary for maximal activity (I). Dialysis invariably lowers the enzyme activity as compared with photolysis, and even prolonged photolysis(More)
Tang and Bonner (16) have described an indoleacetic acid (IAA) oxidase system in pea epicotyls, and also an IAA oxidase inhibitor (17). These findings have been confirmed and extended by others (5-8, 18) and an IAA oxidase has been found in several plants, including beans (18) and pineapple leaf tissue (9). The presence of an inhibitor of IAA oxidation has(More)
We describe a case of a delayed presentation of a traumatic soft tissue mallet injury to the distal phalanx of the hallux in a teenager. Reports of this rare injury are sparse and there is no consensus in their treatment. This injury was treated with open repair of the tendon using a Mitek suture anchor, and stabilization with a 1.2-mm K-wire and extension(More)
Physical and biochemical techniques have clearly demonstrated that a second stage of reaction of the hexosyl-lysines initially formed on non-enzymatic glycosylation of collagen involves the formation of intermolecular crosslinking of the collagen molecules. We have identified an early product of this crosslinking reaction as a putative crosslink and its(More)
Rabbit forelimb tendons incubated for 15 or 21 days at 35 degrees C in the presence of 8 or 24 mg of glucose/ml were shown to change their chemical, biochemical and mechanical characteristics. The tendons treated with glucose contained up to three times as much hexosyl-lysine and hexosylhydroxylysine as did control tendons as judged by assay of(More)
To determine whether hair is excessively glycosylated in diabetes mellitus 4 cm hair samples were taken proximally from behind the ear in 50 white non-diabetics and 46 diabetics. Hair glycosylation was assayed by a modification of the thiobarbituric acid reaction. Blood was taken from the diabetics at the same time for measurement of glycosylated(More)
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