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The ability of non-professional antigen-presenting cells (APC) to process and present antigen to the immune system has been the subject of debate in autoimmunity and tumour immunology. The role of muscle cells in the processing and presentation of antigen to T cells via class I and class II MHC pathways is of increasing interest. Muscle cells are the(More)
The association between HLA-B27 and ankylosing spondylitis could be explained by a "crosstolerance hypothesis". Experimental studies demonstrate immunological crossreactivity between HLA-B27 and antigens found in Gram-negative bacteria, such as Klebsiella. Clinical studies show that an increased frequency of patients with ankylosing spondylitis and uveitis(More)
The binding of rabbit anti-Klebsiella antibodies to tissue-typed lymphocytes obtained from 30 ankylosing spondylitis (AS) patients and 54 healthy subjects has been measured by an enzyme immunoassay method. HLA B27 positive lymphocytes obtained from either AS patients (t = 3.60; p less than 0.001) or healthy subjects (t = 3.77; p less than 0.001) were found(More)
A new family of mathematical functions to fit longitudinal growth data was described in 1978. The ability of researchers to directly use parameters as estimates of age at peak height velocity resulted in them overlooking the possibility of directly calculating these quantities after model estimation. This erratum has corrected three mistakes in the original(More)
  • Mike Baines
  • International journal for vitamin and nutrition…
  • 1982
The relationship between the leucocyte ascorbic acid level and exposure to ethanol has been investigated in a group of patients with alcohol-related illness, and compared with indices of deficiency of other water-soluble vitamins B1 and B2. The degree of exposure to alcohol has been assessed by measurement of the serum activity of gamma-glutamyl transferase(More)