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Magnocellular hypothalamic neurons of the paraventricular (PVN) and supraoptic (SON) nuclei have been shown to contain a wide variety of messenger molecules in addition to vasopressin and oxytocin, including the nitric oxide (NO)-synthesizing enzyme (NOS). In this paper we have investigated the effects of salt loading on the expression of NOS by means of(More)
1 Abstract In this paper, we consider an operational routing problem to decide the daily routes of logging trucks in forestry. The industrial problem is difficult and includes aspects such as pickup and delivery with split pickups, multiple products, time windows, several time periods, multiple depots, driver changes and a heterogeneous truck fleet. In(More)
In this paper we consider the complete supply chain for a large pulp producer in Sweden. The supply chain is divided up in two parts, the pulp production planning problem and the distribution to customers problem. We focus on the overall problem and the interaction between the partial problems and discuss how to solve these simultaneously in a supply chain(More)
Facility location problems form an important class of integer programming problems, with applications in the telecommunication, distribution and transportation industries. In this paper we are concerned with a particular type of facility location problem in which there exist two echelons of facilities. Each facility in the second echelon has limited(More)