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528 Background: The bisphosphonate clodronate (Bonefos) may reduce the incidence of bone metastases by inhibiting tumor-induced osteoclastic resorption of bone. METHODS This randomized,(More)
8056 Background: The bisphosphonate clodronate is effective in the treatment of osteolytic bone metastases at an oral dose of 1600 mg per day. However other doses such as 2400 mg and 3200 mg have(More)
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