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The association between oxidative stress and exposure to environmental chemicals was assessed in a group of Japanese preschool children. The concentrations of 8-hydroxy-2'-deoxyguanosine (8-OHdG), 1-hydroxypyrene (1-OHP), inorganic arsenic (iAs) and monomethylarsonic acid (MMA), and cotinine in spot urine samples, collected from 134 children (3-6 yrs) from(More)
Vulnerability of children to toxic substances is of great concern due to their susceptibility and specific exposure profiles. In this study, we examined urinary 1-hydroxypyrene (1-OHP) levels in 134 kindergarten children and their mothers in order to assess exposure profiles from foods. Mean concentration of 1-OHP in children (0.083 micromol/mol-creatinine)(More)
OBJECTIVES To estimate the level of exposure to polycyclic aromatic hydrocarbons (PAHs) in Japanese children by urinary metabolite analysis and the possible contribution of soil ingestion and environmental tobacco smoke (ETS) to PAHs exposure. METHODS Spot urine samples and questionnaire data were collected from 107 kindergarten children (3-6 yrs) and(More)
We investigated whether or not an intervention of providing food information improves serum Zn levels in ninety-two 18–20-year-old Japanese women. The mean serum Zn level of the participants was 73.09 ± 10.56 (mean ± SD) μg/dL, where 79 % of the participants had lower than the reference Zn level (80 μg/dL) proposed by the Japan Society for Biomedical(More)
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