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We present Swift, a system that combines a novel scripting language called SwiftScript with a powerful runtime system based on CoG Karajan, Falkon, and Globus to allow for the concise specification, and reliable and efficient execution, of large loosely coupled computations. Swift adopts and adapts ideas first explored in the GriPhyN virtual data system,(More)
Scientists, engineers, and statisticians must execute domain-specific application programs many times on large collections of file-based data. This activity requires complex orchestration and data management as data is passed to, from, and among application invocations. Distributed and parallel computing resources can accelerate such processing, but their(More)
Process management is an extremely important concept in both business and scientific communities. Several work-flow management tools have been proposed in recent years offering advanced functionality in various domains. In the business world, workflow vendors offer commercial and customized solutions targeting specific users. In the scientific world,(More)
Grid computing provides the infrastructure necessary to access and use distributed resources as part of virtual organizations. When used in this way, Grid computing makes it possible for users to participate in collaborative and distributed applications such as tele-immersion, visualization, and computational simulation. Some of these applications operate(More)
In this paper we present the Coaster System. It is an automatically-deployed node provisioning (Pilot Job) system for grids, clouds, and ad-hoc desktop-computer networks supporting file staging, on-demand opportunistic multi-node allocation, remote logging, and remote monitoring. The Coaster System has been previously [32] shown to work at scales of(More)
We review the efforts of the Open Grid Computing Environments collaboration. By adopting a general three-tiered architecture based on common standards for portlets and Grid Web Services, we can deliver numerous capabilities to science gateways from our diverse constituent efforts. In this paper, we discuss our support for standards-based Grid portlets using(More)
The Grid approach allows collaborative pooling of distributed resources across multiple domains. However, the benefits of the Grid are limited to those offered by the commodity application development framework used. Several elegant and flexible application development frameworks support only specific Grid architectures, thereby not allowing the(More)
Both medical research and clinical practice are starting to involve large quantities of data and to require large-scale computation, as a result of the digitization of many areas of medicine. For example, in brain research - the domain that we consider here - a single research study may require the repeated processing, using computationally demanding and(More)