Miguel Rocha

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Particle Swarm Optimization (PSO) is a new paradigm of Swarm Intelligence. Particle swarms are a valuable tool to nd optima in a tness landscape in <n, especially useful when dealing with a high number of dimensions and problems where problem speci c information is non-existent. Its rapid convergence and small computational requirements make it a good(More)
Over the last few years a number of methods have been proposed for the phenotype simulation of microorganisms under different environmental and genetic conditions. These have been used as the basis to support the discovery of successful genetic modifications of the microbial metabolism to address industrial goals. However, the use of these methods has been(More)
One of the greatest challenges in Metabolic Engineering is to develop quantitative models and algorithms to identify a set of genetic manipulations that will result in a microbial strain with a desirable metabolic phenotype which typically means having a high yield/productivity. This challenge is not only due to the inherent complexity of the metabolic and(More)
The forecast of Internet traffic is an important issue that has received few attention from the computer networks field. By improving this task, efficient traffic engineering and anomaly detection tools can be created, resulting in economic gains from better resource management. This paper presents a neural network ensemble (NNE) for the prediction of(More)
The Multilayer Perceptrons (MLPs) are the most popular class of Neural Networks. When applying MLPs, the search for the ideal architecture is a crucial task, since it should should be complex enough to learn the input/output mapping, without overfitting the training data. Under this context, the use of Evolutionary Computation makes a promising global(More)
The Genetic Algorithms (GAs) paradigm is being used increasingly in search and optimization problems. The method has shown to be efficient and robust in a considerable number of scientific domains, where the complexity and cardinality of the problems considered elected themselves as key factors to be taken into account. However, there are still some(More)
Systems Biology has taken advantage of computational tools and high-throughput experimental data to model several biological processes. These include signaling, gene regulatory, and metabolic networks. However, most of these models are specific to each kind of network. Their interconnection demands a whole-cell modeling framework for a complete(More)
This article presents three methods to forecast accurately the amount of traffic in TCP=IP based networks: a novel neural network ensemble approach and two important adapted time series methods (ARIMA and Holt-Winters). In order to assess their accuracy, several experiments were held using real-world data from two large Internet service providers. In(More)
In Nature, living beings improve their adaptation to surrounding environments by means of two main orthogonal processes: evolution and lifetime learning. Within the Artificial Intelligence arena, both mechanisms inspired the development of non-orthodox problem solving tools, namely: Genetic and Evolutionary Algorithms (GEAs) and Artificial Neural Networks(More)