Miguel Palafox

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Rapamycin has been used as a clinical immunosuppressant for many years; however, the molecular basis for its selective effects on lymphocytes remains unclear. We investigated the role of two canonical effectors of the mammalian target of rapamycin (mTOR): ribosomal S6 kinases (S6Ks) and eukaryotic initiation factor 4E (eIF4E)-binding proteins (4E-BPs). S6Ks(More)
OBJECTIVE The aim of the present study was to evaluate the quality of integrated child health care management (ICHCM) promoted by the World Health Organization (WHO) after an in-service training course. METHODS The training was carried out in a rural and an urban health unit and in the paediatric ward of the local reference hospital. Tutorial courses were(More)
This study had two aims: to describe the activities of a clinical training unit set up for the integrated management of sick children, and to evaluate the impact of the unit after its first four years of operation. The training unit was set up in the outpatient ward of a government hospital and was staffed by a paediatrician, a family medicine physician,(More)
This paper is focused on a model for the power amplifier considering the memory effects in short terms, this work was developed for periodic signals through Matlab software and was implemented in Simulink. This model for the power amplifier implements a Memory-Polynomial models. Memorypolynomials prove to be both accurate and easy to implement and was(More)
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