Miguel Morente

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BACKGROUND Previous studies suggest that expression of hypoxia markers may be associated with response to antiangiogenic drugs. Thus, we aimed to identify predictors of sunitinib outcome in clear-cell renal cell carcinoma (ccRCC). PATIENTS AND METHODS The expression of eight key proteins related to hypoxia (CAIX, HIF1A, HIF2A, VEGFA, VEGFR1, VEGFR2,(More)
The present study was designed to establish the incidence of colorectal cancer in the province of Guadalajara. During an 8-year-period, 347 cases of colorectal cancer were detected. The adjusted global incidence rate of colorectal cancer was 15.4 per 100,000 population; 17.5 for men and 13.5 for women. The global crude rate was 29.6; 31.4 for men and 27.8(More)
Around 20-30% of Hodgkin Lymphoma (HL) patients do not benefit from standard therapies and finally succumb to their disease. The factors that influence the outcome of HL have not been elucidated, underscoring the demand for the identification of biological risk factors and new therapeutic targets. We analyzed the gene-expression profiles of samples from 29(More)
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