Miguel Cervantes

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Hippocampal theta activity accompanies behaviours such as running, swimming, head movements and spatially orientated responses in the rat. However, whether a relationship between this activity and information processing exists remains unclear. As place-learning depends on hippocampal integrity, whereas cue-learning does not, the hippocampal theta activity(More)
Melatonin reduces pyramidal neuronal death in the hippocampus and prevents the impairment of place learning and memory in the Morris water maze, otherwise occurring following global cerebral ischemia. The cytoarchitectonic characteristics of the hippocampal CA1 remaining pyramidal neurons in brains of rats submitted 120 days earlier to acute global cerebral(More)
This review summarizes the reports that have documented the neuroprotective effects of melatonin against ischemia/reperfusion brain injury. The studies were carried out on several species, using models of acute focal or global cerebral ischemia under different treatment schedules. The neuroprotective actions of melatonin were observed during critical(More)
PURPOSE To analyze the cytoarchitectural characteristics of the remaining pyramidal neurons in the hippocampal CA1 subfield of rats, four months after global cerebral ischemia (GCI) and progesterone treatment. METHODS Dendritic arborization, and density and shape of the dendritic spines of CA1 pyramidal neurons in brains of intact rats, or rats submitted(More)
Consensus on neuroprotection has pointed out the relevance of the long-term morphological and functional evaluation of the effectiveness of putative neuroprotective procedures. In the present study, place learning (Morris water maze) and working memory (eight-arm Olton radial maze) were evaluated in adult male rats 90 days after 15 min of global cerebral(More)
Article history: Received 24 March 2008 Received in revised form 6 August 2008 Accepted 8 August 2008 The objective of this study was to determine the effect of dietary inclusion of benzoic acid on utilization of the macrominerals Ca, P, Mg, K, Na, and Cl in growing pigs. Eighteen barrows, initial BW of 28±1.7 kg, were assigned to 3 diets: a basal diet(More)
The differential characteristics of absolute power in the EEG theta (4–8 Hz) and gamma (30–45 Hz) frequency bands have been analysed in young (18–25 years old, n = 14) and mature adults (45–65 years old, n = 12) during the incidental or intentional behavioural conditions of learning and recalling in a visuospatial task. A printed drawing of a maze including(More)
Electroencephalographic (EEG) and multineuronal activity (MUA) from several brain structures were recorded in 11 adult cats during milk drinking. Milk drinking elicited parietal and hippocampal EEG synchronization and inhibited multiunit discharge in several brain regions. The proportion of EEG synchronization varied considerably between animals, but(More)
In this study, the effects of progesterone (P4) on the immunoreactivity to the neurite growth inhibitor Nogo-A, its receptor (Ng-R), and its effector Rho-A in the rat hippocampus, in association with parameters of spatial learning and memory following global cerebral ischemia, were assessed. Adult male rats were subjected to global cerebral ischemia (15(More)
Multiple unit activity (MUA) was recorded from the ventral tegmental area (VTA) and mesencephalic locomotor region (MLR) during copulatory behavior of freely moving male rats. Simultaneous accelerometric recordings of the copulatory pelvic thrusting performed by the male rat were taken to precisely correlate in time the changes in MUA with well defined(More)