Miguel Ángel Guevara

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Acetylcholine- and serotonin-dependent theta activities have been long proposed to exist. However, several studies have shown that serotonin tends to desynchronise hippocampal EEG activity. Theta activity has been related to the processing of hippocampal place learning. Since the serotonergic system can influence hippocampal theta activity, it could(More)
Hippocampal theta activity is important for the acquisition of spatial information and is strongly influenced and regulated by extra-hippocampal inputs from the synchronising ascending system (SAS), which includes the supramammillary nucleus (SUMn) and the posterior hypothalamic nucleus (PHn). Together these nuclei play an important role in controlling the(More)
The effects of low-dose red wine on cortical electroencephalogram (EEG) and the functional coupling between the frontal and parietal cortices during the first minutes after ingestion were studied. In a first experiment, 38 male volunteers participated in a wine/water challenge protocol in which each subject served as his own control. Wine-induced EEG(More)
The executive functions, which depend on the adequate maturation and functioning of the prefrontal cortex and its connection to posterior zones, follow a process of development as age increases. This work studied changes in the absolute power (AP) of EEG activity recorded in the prefrontal and parietal areas during the performance of the Tower of Hanoi task(More)
The prefrontal cortex is involved in working memory functions, and several studies using food or drink as rewards have demonstrated that the rat is capable of performing tasks that involve working memory. Sexual activity is another highly-rewarding, motivated behaviour that has proven to be an efficient incentive in classical operant tasks. The objective of(More)
Working memory is an executive function that is highly dependent on the functioning of the prefrontal cortex. Several studies using food or drink as rewards have demonstrated that rats are capable of performing tasks that involve working memory. Sexual behavior is another highly-rewarding, motivated behavior that has proven to be an efficient incentive in(More)
This study was aimed to determine the effect of amygdaline inactivation on the sexual motivation of male rats during a T-maze task with a sexual reward. Subjects were chronically implanted with two stainless-steel cannulae that enabled the infusion of tetrodotoxin, a sodium channel blocker, into the left and right basolateral amygdala (BLA). Animals were(More)
INTRODUCTION The metabolism of alcohol and cognitive functions can vary during the menstrual cycle. Also, both alcohol ingestion and hormonal variations during menstruation have been associated with characteristic changes in electroencephalographic (EEG) activity. AIM. To determine whether EEG activity during a working memory task is affected by acute(More)
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