Mieko Otsu

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Plasma cells produce and secrete massive amounts of disulfide-containing antibodies. To accommodate this load on the secretory machinery, the differentiation of resting B cells into antibody-secreting plasma cells is accompanied by a preferential expansion of the secretory compartments of the cells and by an up-regulation of enzymes involved in redox(More)
ond metal is to orchestrate, in part or in full, the two one-electron transfers that subsequently convert H– to H+. The [Fe]-hydrogenase is thus very important for our understanding of H2 biocatalysis in general because it fulfills all the requirements for its activation and scission, the first stages of H2 oxidation by the classic hydrogenases. The three(More)
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