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In contrast to batch cultivation, chemostat cultivation allows the identification of carbon source responses without interference by carbon-catabolite repression, accumulation of toxic products, andContinue Reading
  • Ronald H. W. Maas, Robert Reurd Christophor Bakker, +4 authors Ruud Alexander Weusthuis
  • Biology, Medicine
  • Applied Microbiology and Biotechnology
  • 1 April 2008
  • Conventional processes for lignocellulose-to-organic acid conversion requires pretreatment, enzymatic hydrolysis, and microbial fermentation. In this study, lime-treated wheat straw was hydrolyzedContinue Reading
    The effect of culture age on intra- and extracellular metabolite levels as well as on in vitro determined specific activities of enzymes of central carbon metabolism was investigated during evolutionContinue Reading
  • Mickel Leonardus August Jansen, Pascale A. S. Daran-Lapujade, Johannes H. de Winde, Matthew W. D. Piper, Jack T. Pronk
  • Medicine, Biology
  • Applied and environmental microbiology
  • 1 April 2004
  • Prolonged cultivation (>25 generations) of Saccharomyces cerevisiae in aerobic, maltose-limited chemostat cultures led to profound physiological changes. Maltose hypersensitivity was observed whenContinue Reading