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  • Sorin V. Fedeles, Xin Tian, +7 authors Stefan Somlo
  • Medicine, Biology
  • Nature Genetics
  • 2011 (First Publication: 1 July 2011)
  • Autosomal dominant polycystic liver disease results from mutations in PRKCSH or SEC63. The respective gene products, glucosidase IIβ and SEC63p, function in protein translocation and quality controlContinue Reading
  • Michihiro Mitobe, Takumi Yoshida, Hidekazu Sugiura, Satsuki Shirota, Ken Tsuchiya, Hiroshi Nihei
  • Biology, Medicine
  • Nephron Experimental Nephrology
  • 2005 (First Publication: 22 June 2005)
  • Background/Aims: Defects in klotho gene expression in the mouse result in a syndrome that resembles human aging. We recently identified expression of klotho in a mouse inner medullary collecting ductContinue Reading
  • Y C Yoo, Rei Watanabe, +4 authors Ichiro Azuma
  • Chemistry, Biology, Medicine
  • Biochemical and biophysical research…
  • 1997 (First Publication: 1 August 1997)
  • We examined the activity of bovine lactoferricin (Lfcin-B), a peptide derived from a bovine milk protein lactoferrin (LF-B), to induce apoptosis in THP-1 human monocytic leukemic cells. TreatmentContinue Reading
  • Ryosuke Watanabe, Y C Yoo, +8 authors Ichiro Azuma
  • Biology, Medicine
  • Vaccine
  • 1999 (First Publication: 1 March 1999)
  • We examined the effect of semisynthetic trehalose-6,6 '-dimycolate (TDM) and its synthetic stereoisomeric derivatives (trehalose 6,6'-dicorynomycolates; TDCMs) prepared in oil-in-water (o/w) emulsionContinue Reading