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OBJECTIVES HIV-infected patients using combination antiretroviral therapy (ART) have an increased cardiovascular risk. We aimed to identify the effects of HIV, ART, and lipodystrophy (LD) on carotid artery intima-media thickness (C-IMT), a surrogate measure of atherosclerosis, and arterial stiffness, a marker of cardiovascular risk. DESIGN Case-control(More)
Objective To investigate whether a dog’s superior olfactory sensitivity can be used to detect Clostridium difficile in stool samples and hospital patients. Design Proof of principle study, using a case-control design. Setting Two large Dutch teaching hospitals. Participants A 2 year old beagle trained to identify the smell of C difficile and tested on 300(More)
Dear Editor, The famous physician William Osler once wrote: ‘It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has’. Although this statement was written in the late nineteenth century, inattention to the patient context is still a frequent and under-recognized cause of medical errors [1]. Especially(More)
The aim of this study is to evaluate the effect of different levels of realism of context learning on the prescribing competencies of medical students during the clinical clerkship in internal medicine. Between 2001 and 2007, 164 medical students took part in the prospective explorative study during their clinical clerkship in internal medicine at the VU(More)
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