Michelle Tiszavari

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OBJECTIVE To investigate the hormones participating in early follicular development and hypothalamic neurotransmitters in rats during adulthood. DESIGN Experimental basic study. SETTING University animal laboratory. ANIMAL(S) Twenty-three neonatal rats injected with single subcutaneous injection of estradiol valerate (EV), testosterone propionate(More)
Growth and differentiation of ovarian follicles are regulated by systemic and local factors, which may include acetylcholine (ACh). Granulosa cells (GCs) of growing follicles and luteal cells produce ACh and in cultured GCs it exerts trophic actions via muscarinic receptors. However, such actions were not studied in vivo. After having established that rat(More)
To understand the impact of exposure to steroids in the early step of ovary development (a stage occurring in uterus in humans), we studied neonatal exposure to estradiol valerate (EV) in rats regarding polycystic ovary (PCO) development as well as expression of androgen receptor (Ar) and anti-Müllerian hormone (AMH), a marker of ovarian follicular(More)
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