Michelle Nisolle

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OBJECTIVE To review the histogenesis of peritoneal, ovarian, and rectovaginal endometriotic lesions. DESIGN The comparison of morphologic, morphometric, and histochemical data observed in each type of lesion. SETTING A university hospital department of gynecology. PATIENT(S) Patients complaining of infertility or pelvic pain with laparoscopically(More)
Angiogenesis is likely to be involved in the pathogenesis of endometriosis. According to the transplantation theory, when the exfoliated endometrium is attached to the peritoneal layer, the establishment of a new blood supply is essential for the survival of the endometrial implant and development of endometriosis. From the known angiogenic factors,(More)
OBJECTIVE To evaluate the implantation of menstrual endometrium and the early stages of evolution of endometriotic lesions. DESIGN Experimental prospective study. SETTING An academic research environment. ANIMALS Ten nude mice. INTERVENTION(S) A minilaparotomy was performed to place fresh human menstrual endometrial samples in the peritoneal cavity.(More)
BACKGROUND Thiamine (vitamin B1) is an essential molecule for all life forms because thiamine diphosphate (ThDP) is an indispensable cofactor for oxidative energy metabolism. The less abundant thiamine monophosphate (ThMP), thiamine triphosphate (ThTP) and adenosine thiamine triphosphate (AThTP), present in many organisms, may have still unidentified(More)
OBJECTIVE To evaluate the ovarian response to stimulation conducted for IVF treatment in women who have undergone conservative surgery for endometriomas. DESIGN Retrospective study with prospective selection of participants and controls. SETTING University infertility clinic. PATIENT(S) A series of 374 women who underwent in vitro fertilization (IVF).(More)
OBJECTIVE To compare histologic and ultrastructural characteristics of fresh and frozen-thawed human ovarian cortical tissue grafted into nude mice. DESIGN Experimental prospective study. SETTING An academic research environment. PATIENT(S) Ovarian biopsy specimens were obtained from 13 women undergoing laparoscopy for tubal ligation or infertility.(More)
BACKGROUND There is currently no consensus about indications for surgery for infertility associated with colorectal endometriosis. The aim of this study was to evaluate cumulative pregnancy rates (CPRs) after ICSI-IVF cycles in patients with colorectal endometriosis and to identify determinant factors of fertility outcome. METHODS Prospective longitudinal(More)
A series of 231 cases of deep-infiltrating endometriosis of the rectovaginal septum is presented. Laparoscopic procedures with excision of deep fibrotic endometriotic nodules were performed in all cases. In three cases, the bowel lumen was entered. No other peri-operative complications were observed. Three cases of urinary retention were reported. The(More)
The management of large endometriomas was described in a series of 814 patients. Combined therapy using gonadotrophin-releasing hormone agonist (GnRHa) and carbon dioxide laser laparoscopy was proposed. Drainage and GnRHa for 12 weeks provoked a reduction of the endometrioma size up to 50% of the initial value. After vaporization of the internal wall, a(More)
OBJECTIVE To present data from 18 cases of ureteral endometriosis. DESIGN Prospective clinical study. SETTING Department of gynecology at a university hospital. PATIENT(S) Four hundred and five patients with severe dysmenorrhea or deep dyspareunia due to a rectovaginal endometriotic (adenomyotic) nodule. INTERVENTION(S) Patients were prospectively(More)