Michelle Moosang

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OBJECTIVE To determine the prevalence and predictors of microalbuminuria (MA) (urine albumin-creatinine ratios (ACRs) of 30-300 µg/mg) in children with homozygous sickle cell (Hb SS) disease in Jamaica. PATIENTS AND METHODS 244 children with Hb SS disease were screened for MA. Blood samples and a retrospective review of patient records were used to(More)
Although there is some evidence that epilepsy is more common in Sickle Cell Disease (SCD), we sought to establish the incidence rates, risk factors for and specific types of seizures in a SCD cohort followed from birth, and how seizure occurrence affects morbidity and mortality. We examined all records of persons in the Jamaica cohort Study of Sickle Cell(More)
The world-wide epidemic of Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) has led to an increase in the number of HIV positive children, mainly through perinatal transmission. HIV/AIDS can lead to severe childhood malnutrition (SCM) and has been noted as an increasingly common cause of secondary SCM. In this context, it is(More)
Acute hemorrhagic leukoencephalitis (AHLE), otherwise known as Hurst’s Disease, is a rare, rapidly progressive and usually fatal demyelinating condition affecting the central nervous system. It is usually preceded by an upper respiratory tract infection and is thought by many authors to be a hyperacute form of post infectious encephalomyelitis. It was(More)
Chronic transfusion therapy is the treatment of choice for preventing stroke recurrence in children with sickle cell disease (SCD). The majority of children affected by this devastating complication live in the developing world where access to regular blood transfusions may be impractical. Since 2000, in the absence of regular blood supplies, all children(More)
OBJECTIVE Penicillin prophylaxis is important in the defence against invasive pneumococcal disease in sickle cell disease (SCD). Penicillin may be administered by the oral route or by the intramuscular (IM) route. Compliance with the oral route, although difficult to assess, has been reported to be highly variable and often poor. We sought to determine the(More)
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