Learn More
Rear-end collisions account for almost 30% of automotive crashes. Rear-end collision avoidance systems (RECASs) may offer a promising approach to help drivers avoid these crashes. Two experiments performed using a high-fidelity motion-based driving simulator examined driver responses to evaluate the efficacy of a RECAS. The first experiment showed that(More)
As use of in-vehicle information systems (IVISs) such as cell phones, navigation systems, and satellite radios has increased, driver distraction has become an important and growing safety concern. A promising way to overcome this problem is to detect driver distraction and adapt in-vehicle systems accordingly to mitigate such distractions. To realize this(More)
Teen drivers are at high risk for car crashes, especially during their first years of licensure. Providing novice teen drivers and their parents with a means of identifying their risky driving maneuvers may help them learn from their mistakes, thereby reducing their crash propensity. During the initial phase of learning, adult or parental supervision often(More)
OBJECTIVES We examined whether feedback from an event-triggered video intervention system reduced the number of safety-relevant driving errors made by newly licensed adolescents. METHODS We used a 1-group pretest-posttest quasi-experimental design to compare the rate of coachable error events per 1000 miles for 18 drivers who were aged 16 years. The(More)
OBJECTIVE The purpose of this study was to characterize the innervation of the levator ani muscles in the female squirrel monkey and to investigate its usefulness as an animal model of pelvic organ prolapse. STUDY DESIGN Eleven nulliparous female squirrel monkeys with no pelvic organ prolapse were used in this study. Detailed pelvic dissections were(More)
OBJECTIVE The purpose of this study was to characterize the spinal distribution of afferent and efferent pathways that innervate the levator ani (LA) muscle in the female squirrel monkey. STUDY DESIGN Cholera toxin B (CTB) was injected unilaterally into the LA muscle of 5 monkeys to identify primary sensory neurons in the dorsal root ganglia (DRG) and(More)
Traffic Safety Administration, in the interest of information exchange. The opinions, findings and conclusions expressed in this publication are those of the author(s) and not necessarily those of the Department of Transportation or the National Highway Traffic Safety Administration. The United States Government assumes no liability for its content or use(More)
OBJECTIVE Preeclampsia (preE), a syndrome of hypertension, proteinuria, and edema, has many elusive triggers. The renin-angiotensin system has been implicated in preE pathogenesis. In this study, we test the hypothesis that (pro)renin levels are increased in preE patients and that levels of (pro)renin and (pro)renin receptor ((P)RR) are elevated in a rat(More)
INTRODUCTION Preeclampsia (preE) is characterized by abnormal placentation. Marinobufagenin (MBG), a cardiotonic steroid (CTS), inhibits the function of cytotrophoblast cells (CTBs). We demonstrated that CTSs induce anti-angiogenic and anti-proliferative effects in Sw-71 CTBs. This study tests that CTSs induce apoptotic and stress signaling. METHODS Human(More)
INTRODUCTION AND HYPOTHESIS The aim was to test the hypothesis that the pelvic outlet diameter (POD) is associated with pelvic organ prolapse (POP) in squirrel monkeys. METHODS Magnetic resonance images (MRI) were obtained from 55 females with and without POP. Commercial software was used by two observers to measure the POD. POD, age, parity, and weight(More)