Michelle Grayson

Learn More
S21 Chagas disease is arguably the archetypal neglected disease. Millions of people — the vast majority in Latin America — are infected, yet it is seldom discussed. It has struggled to achieve even a fraction of the notoriety of other neglected diseases, such as malaria. Its prevalence in immigrants to Spain, Portugal, the United States and other parts of(More)
S40 A thalamic input to the nucleus accumbens mediates opiate dependence Y. Zhu et al. Pain is unpleasant but necessary. It signals danger, preventing us from harming ourselves, and alerts us to damage to our bodies. Yet for many people, their pain system is out of alignment. Too much pain is crippling and can make everyday living an agony. Even ‘good’ pain(More)
Editorial advisor Felix Cheung COVER ART: NIK SPENCER When the topic of traditional Asian medicine was first mooted, we were sceptical. To a magazine based in Europe and steeped in the history of science, there is much about traditional Asian medical practice that seems mystical and pseudoscientific. Other than well known success stories — artemisinin for(More)
S17 RESEARCH 4 big questions The puzzles still facing researchers As we approach the bicentenary of James Parkinson’s seminal paper on what he called “shaking palsy”, it is clear that our understanding of Parkinson’s disease has become significantly more nuanced (see page S2). Alongside the characteristic physical traits such as rigidity, tremor and(More)
Editor-in-Chief Philip Campbell Cover art: Gavin Potenza Drought has long been a scourge of humanity and a factor in war and conflict. The current crisis in Syria, for example, comes in the wake of one of its worst ever droughts. Periodic droughts occur because of global temperature cycles in the oceans and atmosphere. But although we understand the causes(More)
Michelle Grayson is senior supplements editor at Nature. Clearer patient phenotypes will help researchers to identify more specific biomarkers, which can also be used to stratify patients for clinical testing of targeted drugs. Attempts to develop biomarkers for IBS have been disappointing. Breath tests and diagnostics that involve serum biomarkers are in(More)
S165 RESEARCH 4 big questions Directions for future research They can come on slowly in adulthood or arrive suddenly and fatally in infancy. Their symptoms can include seizures and dementia, enlargement of the spleen and liver, and abnormal bone formation. They are rare, yet vary in frequency: the most common occur once in every 50,000 or so live births,(More)
SUBSCRIPTIONS AND CUSTOMER SERVICES For UK/Europe (excluding Japan):Nature Publishing Group, Subscriptions, Brunel Road, Basingstoke, Hants, RG21 6XS, UK. Tel: +44 (0) 1256 329242. Subscriptions and customer services for Americas – including Canada, Latin America and the Caribbean: Nature Publishing Group, 75 Varick St, 9th floor, New York, NY 10013-1917,(More)
S82 Q&A Individual approach Jane Harding balances the pros and cons of New Zealand’s system and its focus on individual researchers Society benefits enormously from scientific research. We get new technologies, live longer and healthier lives, and gain deeper knowledge of our planet and the Universe. The issue of how to evaluate the fruits of research(More)
EDITORIAL: Herb Brody, Michelle Grayson, Rebecca Dargie, Victoria Kitchener, Felix Cheung, Jiajun He. Stephen Pincock. EDITORIAL SUPPORT: Nobuko Miyairi, Larissa Kogleck. ART & DESIGN: Wesley Fernandes, Alisdair Macdonald, Andrea Duffy, Denis Mallet, Chris Gilloch. WEB & DATA: Bob Edenbach, Olivier Lechevalier, Yuxin Wang, Naomi Nakahara, Masamichi Wada,(More)