Micheline Van Caillie-Bertrand

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ABSTRACT. Plasma selenium concentration and glutathione peroxidase activity in red blood cells were determined in subjects from different age groups. The selenium level (mean ± SD) found in infancy (0 to 6 months) was 2 ± 0.6 /μg/dl, with the lowest value of 1 /μg/dl observed in a 4- month-old infant. These levels were significantly lower (p<0.001) than the(More)
The selenium content of commercial infant formulae, processed milk and beikost was measured by hydride generation atomic absorption spectrometry after previous wet acid digestion. The median daily intake by infants (1–6 months) fed milk, soya or cereal-based infant formulae was 3.0–7.8 μg/day; lower than the mean daily intake by Belgian breast-fed infants(More)
Phenylketonuric (PKU) subjects have a limited supply of selenium (Se) in their phenylalanine-restricted diet. A Se repletion (1 μg Se/kg/day)/depletion study was conducted in PKU children to determine the effect of Se on thyroid function parameters. The initial plasma Se concentration (mean±SD: 0.26±0.12 μmol/L, p<0.00003, n=10) and glutathione peroxidase(More)
Type I 5′-deiodinase was recently characterized as a selenocysteine-containing enzyme in humans and other mammals. Up to now, the effect of selenium (Se) supplementation on thyroid hormone metabolism in humans has only been reported in the very peculiar nutritional environment of Central Africa, where combined severe iodine and Se deficiency occurs. In this(More)
From 1/34 to 8/86 130 infants were referred because of an event of prolonged apnea, hypotonia and cyanosis or pallor. The study protocol consisted in a night polygrafic recording (P.R.). A metabolic, neurological, toxicoloyical, gastrointestinal and cardiological work up.Gastroesophageal reflux was suspected in 73/130 patients. In 48 patients 24-h intra(More)
Experiments were conducted to evaluate the extent to which element binding of locust bean gum (LBG) affects the availability of calcium, iron, and zinc in the gut. Infant formula was supplemented with increasing amounts of LBG and subjected to an intraluminal digestion procedure. Element binding was measured by eliminating the complexes by twofold(More)
The use of purified aminoacid mixtures in children with inborn errors of metabolism on protein restricted diets has led to a reduction of the intake of most essential micronutrients. As an integral part of glutathione peroxidase(GSH-Px), se is considered to be essential:it should thus be provided in adequate amounts as a biologically active compound as to(More)
In Western Countries, the major sources of selenium (SE) are protein rich products such as meat, fish, eggs and bread. One could expect that in patients with phenylketonuria on a protein restricted diet, the SE intake will be dramatically reduced. To objectify this, we decided to measure the daily intake of 5 PKU children's, aged 7 to 19 year, during a PKU(More)
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