Among 30 Parkinson's disease patients who received high frequency stimulation of the subthalamic nucleus, 5 developed remarkable disorders of mood or sexual behavior after the implant. We describe 2 men who developed mania and hypersexuality a few days after the implant that lasted for some months and then gradually disappeared spontaneously.
Antipsychotic-induced extrapyramidal adverse effects continue to be a serious problem in the treatment of psychotic disorders. While the pathophysiology of these adverse effects is not well understood, much recent research has focused on improving our ability to use available pharmacotherapy in the most effective and least toxic manner. Acute dystonic… (More)
OBJECTIVE The aim of the present study was to find out the extent of hostility and violence and the factors that are associated with such hostility and violence in a psychiatric intensive care unit. METHODS Retrospective analysis of data prospectively collected in a 6-year period. RESULTS No hostility was observed in 56.1%, hostility in 40.9%, and… (More)
The relationship between Asperger syndrome (AS) and schizophrenia is still unclear. An unanswered question is, do hallucinations or delusions per se justify a diagnosis of schizophrenia when these symptoms appear in subjects with AS? The aims of the present study were: (1) to review the characteristics of thought disorder in AS and schizophrenia; (2) to… (More)
The absence of ejaculation in two patients treated with risperidone is described. This side-effect has rarely been reported. The mechanism responsible for ejaculation dysfunction in risperidone treated patients is unclear, but might be due to the alpha1-adrenergic antagonist action of the drug.
The aim of this observational study was to assess the rates of aggressive and violent behavior in patients admitted to an Italian emergency psychiatric unit and to explore possible risk factors for patient violence. In a population of 313 consecutive patients, we considered aggressive or violent behavior, rated according to a hierarchy from no aggressive… (More)
To date, clozapine is the only antipsychotic agent that has established itself as having minimal, if any, risk of tardive dyskinesia (TDk). In patients with TDk, clozapine permits the dyskinesia to disappear in approx. 50% of cases, particularly those with dystonic features, i.e. tardive dystonia (TDt) (Gardos, 1999). Unfortunately, clozapine is not always… (More)
In a population of 200 consecutive inpatients with a history of at least 3 months' total cumulative neuroleptic exposure, the prevalence of tardive dystonia (TDt) was 4%, higher than previously reported. The prevalence of tardive dyskinesia (TDk) was 22%. Patients with TDt did not differ in demographic or clinical variables from nondyskinetic patients. In… (More)