Michele Raja

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Among 30 Parkinson's disease patients who received high frequency stimulation of the subthalamic nucleus, 5 developed remarkable disorders of mood or sexual behavior after the implant. We describe 2 men who developed mania and hypersexuality a few days after the implant that lasted for some months and then gradually disappeared spontaneously.
Impulsive and compulsive behaviors, including pathologic gambling, hypersexuality, compulsive shopping, compulsive eating, excessive engagement in hobbies, punding, and Dopamine Dysregulation Syndrome (DDS), are increasingly reported serious side-effects of dopaminergic medication, used in the treatment of Parkinson's Disease (PD) and other disorders.(More)
OBJECTIVE The aim of the present study was to find out the extent of hostility and violence and the factors that are associated with such hostility and violence in a psychiatric intensive care unit. METHODS Retrospective analysis of data prospectively collected in a 6-year period. RESULTS No hostility was observed in 56.1%, hostility in 40.9%, and(More)
Aripiprazole, an antipsychotic recently introduced for clinical use, may worsen psychotic symptoms, even at low dose. In other cases, aripiprazole may exercise an antipsychotic action and induce extrapyramidal side-effects, even at low dose. There are no clear-cut criteria to differentiate the patients whose psychotic symptoms will or will not respond to(More)
Clozapine is the best treatment option in several clinical circumstances, including treatment-resistant schizophrenia, non treatment-resistant schizophrenia, suicide risk in schizophrenia spectrum disorders, aggressiveness or violence in psychiatric patients, psychosis in Parkinson's disease, prevention and treatment of tardive dyskinesia. However,(More)
  • Michele Raja
  • European archives of psychiatry and clinical…
  • 1995
In a population of 200 consecutive inpatients with a history of at least 3 months' total cumulative neuroleptic exposure, the prevalence of tardive dystonia (TDt) was 4%, higher than previously reported. The prevalence of tardive dyskinesia (TDk) was 22%. Patients with TDt did not differ in demographic or clinical variables from nondyskinetic patients. In(More)
The aims of the present study were to examine clinical, personality, and sociodemographic predictors of suicide risk in a sample of inpatients affected by major affective disorders. The participants were 74 inpatients affected by major depressive disorder or bipolar disorder-I. Patients completed a semi-structured interview, the Beck Hopelessness Scale, the(More)
The relationship between Asperger syndrome (AS) and schizophrenia is still unclear. An unanswered question is, do hallucinations or delusions per se justify a diagnosis of schizophrenia when these symptoms appear in subjects with AS? The aims of the present study were: (1) to review the characteristics of thought disorder in AS and schizophrenia; (2) to(More)
BACKGROUND The relationship between Autism Spectrum Disorders (ASDs) and schizophrenia is currently unclear. We aimed to (a) assess psychotic symptoms in a consecutive series of adult patients with ASDs, (b) evaluate the comorbidity diagnosed to account for the concurrent psychotic symptoms in patients with ASDs, and (c) compare the clinical features(More)