Michele Napolitano

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This paper combines a state-of-the-art method for solving the three-dimensional preconditioned Navier–Stokes equations for compressible flows with an immersed boundary approach, to provide a Cartesian-grid method for computing complex flows over a wide range of the Mach number. Moreover, a flexible local grid refinement technique is employed to achieve high(More)
Abstract. This paper combines a state-of-the-art method for solving the preconditioned compressible Navier–Stokes equations accurately and efficiently for a wide range of the Mach number with an immersed-boundary approach which allows to use Cartesian grids for arbitrarily complex geometries. The method is validated versus well documented test problems for(More)
Act-2 is a cytokine that belongs to a superfamily of structurally related proteins. Act-2 expression is rapidly induced in T cells, B cells, and monocytes upon mitogenic stimulation. The Act-2 genomic locus is on chromosome 17q. The exons and exon/intron splice junctions have been sequenced, as have the sequences upstream of exon 1. A classical TATA box is(More)
We have identified an immune activation gene, denoted Act-2, by differential hybridization screening of an activated T-cell library. The gene is induced rapidly after T-cell activation with phytohemagglutinin, B-cell activation with Staphylococcus aureus Cowan I, and monocyte activation with lipopolysaccharide. We have isolated a cDNA containing the(More)
We report on measurements of hadronic and leptonic cross sections and leptonic forwardbackward asymmetries performed with the L3 detector in the years 1993–95. A total luminosity of 103 pb−1 was collected at centre-of-mass energies √ s ≈ mZ and √s ≈ mZ±1.8 GeV which corresponds to 2.5 million hadronic and 245 thousand leptonic events selected. These data(More)
Macrophage inflammatory protein 1 alpha (MIP-1 alpha) is a potent stem cell inhibitor and a member of a large and expanding family of related cytokines. In an effort to understand the molecular basis of the activities of MIP-1 alpha, we have sought to characterize the cellular receptors for this molecule. Our results demonstrate the presence of abundant(More)
This chapter is divided into two sections, the first dealing with a novel immune activation gene, denoted Act-2. This gene encodes a secreted protein that may represent a new cytokine. The Act-2 protein shares significant homology with proteins in two related families of small secreted proteins. Act-2 is rapidly synthesized by activated T cells, B cells and(More)