Michele Mondoni

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We studied the urinary excretion of the isoprostane 8-iso-prostaglandin F(2alpha) as an index of in vivo oxidant stress, and the production of leukotriene (LT) B(4) (LTB(4)) by neutrophils in subjects with chronic obstructive pulmonary disease (COPD) and normal subjects. Overnight urinary excretion of the isoprostane was significantly higher in patients(More)
We studied the urinary excretion of the isoprostane 8-iso-Prostaglandin F 2α , as an index of in vivo oxidant stress, and the production of leukotriene B 4 (LTB 4) by neutrophils in chronic obstructive pulmonary disease (COPD) and normal subjects. Overnight urinary excretion of the isoprostane resulted significantly higher in COPD patients than in controls,(More)
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