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  • Michele Columbo, Elliot Horowitz, +6 authors Lawrence M. Lichtenstein
  • Biology, Medicine
  • Journal of immunology
  • 1992 (First Published: 15 July 1992)
  • The gene product of the steel locus of the mouse represents a growth factor for murine mast cells and a ligand for the c-kit proto-oncogene receptor, a member of the tyrosine kinase receptor class ofContinue Reading
    Forskolin, a diterpene compound isolated from the roots of Coleus forskohlii, activates adenylate cyclase in membranes from a variety of mammalian tissues. We found that forskolin (10(-7) to 3 XContinue Reading
  • Michele Columbo, Elliot Horowitz, Vincenzo Patella, Anne Kagey-Sobotka, Floyd H. Chilton, Lawrence M. Lichtenstein
  • Medicine
  • The Journal of allergy and clinical immunology
  • 1993 (First Published: 1 August 1993)
  • BACKGROUND IgE-mediated stimulation of human basophils and lung mast cells causes the synthesis of larger amounts of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine (1-acyl-2-acetyl-GPC) thanContinue Reading
  • Michele Columbo, Elliot Horowitz, Anne Kagey-Sobotka, Lawrence M. Lichtenstein
  • Biology, Medicine
  • Clinical immunology and immunopathology
  • 1996 (First Published: 1 October 1996)
  • Using pharmacologic agents, we explored the mechanism by which a potent neuropeptide, substance P, induces the secretion of histamine from human skin mast cells and compared their effects onContinue Reading
  • Michele Columbo, Maurizio Taglialatela, +4 authors G Marone
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 1992
  • Maitotoxin (MTX) is a potent marine toxin which stimulates several Ca(++)-dependent processes presumably through an increase in Ca++ permeability. We have examined the effect of MTX on the release ofContinue Reading