Michele Baioni

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We attempted to analyze whether the use of high-dose cyclophosphamide (CTX 7g/m2, group A) plus hematopoietic growth factor (G-CSF) or G-CSF alone (10 microg/Kg, group B) as a mobilizing regimen, could result in harvesting different numbers of CD34+ cells, committed progenitors and CD34+ cells subsets. The number of CD34+ cells considered as the target for(More)
OBJECTIVES The objective was to investigate the prognostic value of plasma lactate in patients with acute pulmonary embolism (PE). METHODS This was a retrospective study at the emergency department (ED) of a third-level teaching hospital. The authors considered consecutive patients with a diagnosis of PE established by lung scan or spiral computed(More)
BACKGROUND Recently, some prognostic models for acute pulmonary embolism (PE) have been proposed. We investigated whether the Pulmonary Embolism Severity Index (PESI) and the European Society of Cardiology (ESC) prognostic approaches result in different prognoses. METHODS Consecutive adult patients with acute PE were included. According to the ESC(More)
STUDY OBJECTIVE We investigate the prognostic value of plasma lactate levels in patients with acute pulmonary embolism. METHODS We studied adult patients with symptomatic, objectively confirmed pulmonary embolism presenting to a single emergency department. Plasma lactate and troponin I levels were tested at presentation. We considered lactate values(More)
SUMMARY We verified the possibility of collecting large amounts of peripheral blood stem cells (PBSCs) to support three courses of adjuvant high-dose dense chemotherapy (HDDC) with high-dose epirubicin, preceded by dexrazoxane, and high-dose paclitaxel, in patients with high-risk breast cancer (>/=9 positive nodes). The mobilizing regimen consisted of(More)
Patients and methods Study patients: 11 consecutive adults with a diagnosis of pneumoperitoneum by CT. Control patients: 11 consecutive adults with severe acute abdominal pain with a diagnosis other than pneumoperitoneum by CT. US examination has been performed with a convex and a linear probe using the following scans: epigastrium, right and left(More)
BACKGROUND AND OBJECTIVE The aim of the present study was to evaluate the correlation between the number of CD34+ cells transfused and the duration of hypoplasia, and the relationship between various CD34+ subsets (CD34+/33-; CD34+/38-; CD34+/ HLA-DR-; CD34+/Thy-1+) and engraftment kinetics in a series of patients with breast cancer treated with high doses(More)
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