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OBJECTIVE Stroke is a major cause of adult-onset disability and dependency. We investigated whether EEG parameters are of prognostic value for functional outcome 6 months after ischemic stroke. METHODS One-hundred and ten patients presenting with acute ischemic stroke and persistent neurological deficits at EEG recording were incrementally included.(More)
OBJECTIVE Persistent absence of the median nerve N20 response in patients suffering from postanoxic coma after a cardiac arrest is invariably associated with a poor outcome. Preservation of the N20 response, however, does not indicate a good recovery. We wish to improve our understanding on this issue. METHODS We discuss the limited specificity of the(More)
OBJECTIVE To evaluate the value of continuous electroencephalography in early prognostication in patients treated with hypothermia after cardiac arrest. DESIGN Prospective cohort study. SETTING Medical intensive care unit. PATIENTS Sixty patients admitted to the intensive care unit for therapeutic hypothermia after cardiac arrest. INTERVENTION None.(More)
The objective of this review was to compare and to discuss the results of studies that investigated the ability of drugs to improve motor recovery after stroke by influencing dopamine, norepinephrine, or serotonin concentrations in the brain. A systematic literature search up to January 2009 was conducted in MEDLINE, Pubmed, EMBASE and in the database of(More)
OBJECTIVE To investigate reproducibility and clinical relevance of quantitative EEG parameters in ischemic cerebrovascular disease. METHODS EEG was recorded in 31 patients suffering from subacute ischemic cerebrovascular disease. Ten age-matched control subjects were included as a reference group. Intra-recording, intrarater and interrater reproducibility(More)
Investigations of (sub-)acute ischaemic stroke (IS) employing quantitative electroencephalographic (QEEG) methods, in concert with other assessments, are reviewed. Numerous outcomes from hundreds of patients collectively indicate that (sub-)acute QEEG indices from standard systems can uniquely inform clinical management, particularly prognostication of(More)
There is increasing experimental evidence that neuronal synchronization is necessary for the large-scale integration of distributed neuronal activity to realize various time-dependent coherent neuronal assemblies in the brain. Phase synchronization seems a promising candidate to quantify the time-dependent, frequency specific, synchrony between(More)
OBJECTIVE Removal of brain tissue showing high frequency oscillations (HFOs; ripples: 80-250Hz and fast ripples: 250-500Hz) in preresection electrocorticography (preECoG) in epilepsy patients seems a predictor of good surgical outcome. We analyzed occurrence and localization of HFOs in intra-operative preECoG and postresection electrocorticography(More)
OBJECTIVE Event-related desynchronization (ERD) or synchronization (ERS) refers to the modulation of any EEG rhythm in response to a particular event. It is typically quantified as the ratio between a baseline and a task condition (the event). Here, we focused on the sensorimotor mu-rhythm. We explored the effects of different baselines on mu-power and ERD(More)
OBJECTIVE Assessment of event-related desynchronization (ERD) may assist in predicting recovery from stroke and rehabilitation, for instance in BCI applications. Here, we explore the temporal evolution of ERD during stroke recovery. METHODS Ten stroke patients and eleven healthy controls were recruited to participate in a hand movement task while EEG was(More)