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Oxaliplatin as single agent in previously untreated colorectal carcinoma patients: a phase II multicentric study.
BACKGROUND Oxaliplatin is a new cytotoxic agent from the diaminocyclohexane family with proven antitumor activity against colon cancer cell lines. Activity in patients with colorectal carcinomaExpand
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Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo.
Tenatoprazole is a prodrug of the proton pump inhibitor (PPI) class, which is converted to the active sulfenamide or sulfenic acid by acid in the secretory canaliculus of the stimulated parietal cellExpand
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Tenatoprazole, a novel proton pump inhibitor with a prolonged plasma half‐life: effects on intragastric pH and comparison with esomeprazole in healthy volunteers
Background : Proton pump inhibitors control gastric acidity better during the day than at night, when nocturnal acid breakthrough can occur. Tenatoprazole is a novel proton pump inhibitor with aExpand
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A comparative study of the early effects of tenatoprazole 40 mg and esomeprazole 40 mg on intragastric pH in healthy volunteers
Background : Tenatoprazole is a novel proton pump inhibitor with a seven‐hour plasma half‐life.
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Double-blind dose-response multicenter comparison of fedotozine and placebo in treatment of nonulcer dyspepsia
The efficacy and safety of the peripheral kappa-receptor agonist fedotozine was investigated in a double-blind, placebo-controlled, dose-ranging study involving 146 patients with nonulcer dyspepsiaExpand
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Comparison of the effects of fasting morning, fasting evening and fed bedtime administration of tenatoprazole on intragastric pH in healthy volunteers: a randomized three‐way crossover study
Background  The effectiveness of proton pump inhibitors is influenced by meals and administration time.
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[Comparative effects of ricinoleic acid and senna on orocecal and oroanal transit time in healthy subjects. Application of the salacylazosulfapyridine method].
The appearance in plasma of sulphapyridine after oral administration of salicylazosulphapyridine (Salazopyrin) was shown to be useful for measuring the orocecal transit time in normal subjects. TheExpand
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sodium salt monohydrate of S-tenatoprazole and therapeutic use
The invention relates to the monohydrated sodium salt of tenatoprazole represented by the formula:. Therapeutic application for the treatment of digestive pathologies