Michel Grimaître

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BACKGROUND The beneficial effect of topical colchicine therapy for actinic keratoses has already been described in 1968. OBJECTIVE To confirm that the application of a 1% colchicine gel is a safe and effective treatment for actinic keratoses. METHODS Twenty patients were included in a double-blinded protocol. They all had actinic keratoses on the scalp,(More)
Bullous pemphigoid (BP) is an autoimmune blistering disorder that may very rarely occur in childhood. We describe a 9-month-old child who developed bullous pemphigoid while she was being treated for presumptive atopic eczema with a homeopathic regimen comprising sulfur, mercury, cantharides, and Rhus (Toxicodendron). She had generalized bullae and a(More)
The T cell-dependent B cell response in vivo occurs in organized microenvironments. Alternative routes exist in that early plasma cells are generated in the T zone while others emerge later from the germinal center (GC) reaction. We investigated whether B cell stages resembling those defined in vivo/ex vivo might be induced in an in vitro system in which(More)
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