Michal Novotny

Learn More
In the first of two experiments, rats with left or right parietal lesions and controls were tested in place and landmark navigation in the water maize. Right parietal lesions resulted in deficits in both tasks, but especially landmark navigation. Lateralized effects appeared mainly in latency to find the platform. Experiment 2 investigated the role of the(More)
Although articulatory deficits represent an important manifestation of dysarthria in Parkinson's disease (PD), the most widely used methods currently available for the automatic evaluation of speech performance are focused on the assessment of dysphonia. The aim of the present study was to design a reliable automatic approach for the precise estimation of(More)
Although speech disorder is frequently an early and prominent clinical feature of Parkinson's disease (PD) as well as atypical parkinsonian syndromes (APS) such as progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), there is a lack of objective and quantitative evidence to verify whether any specific speech characteristics allow(More)
Bernstein and Putnam (1986) recently developed the Dissociative Experiences Scale (DES), a reliable and valid measure of dissociative experiences. The purpose of this study was to determine the relationship of the DES to other measures of psychopathology and cognitive functioning. Seventy-six female and 43 male university students were administered the DES,(More)
Patterns of volatile metabolites in urine, as obtained by glass-capillary gas chromatography, were investigated by use of a nonparametric pattern-recognition method, in an effort to detect abnormalities associated with diabetes. We used threshold logic unit analysis on a data set consisting of normal subjects and those with diabetes mellitus, and could(More)
In this work we present the method that we have adopted in order to leave in search of the speaker through different measures of jitter and shimmer are measures of the fundamental frequency and of amplitude variations cycle to cycle. We have used these two indices as they characterize some aspects concerning the Voice individuals, so it helps us to have a(More)
We present a computational framework to analyze MALDI-TOF mass spectrometry data for quantitative comparison of peptides and glycans in serum. In particular, we introduce an algorithm that detects peaks that are differentially abundant in a subgroup of patients. The method is applied to identify candidate biomarkers in serum samples of 203 participants from(More)
It is currently unknown whether speech and limb motor effectors in Parkinson's disease (PD) are controlled by similar underlying brain processes. Based on computerized objective analysis, the aim of this study was to evaluate potential correlation between speech and mechanical tests of upper limb motor function. Speech and upper limb motor tests were(More)
BACKGROUND Although increased nasality can originate from basal ganglia dysfunction, data regarding hypernasality in Parkinson's disease (PD) and Huntington's disease (HD) are very sparse. The aim of the current study was to analyze acoustic and perceptual correlates of velopharyngeal seal closure in 37 PD and 37 HD participants in comparison to 37 healthy(More)
Recently, based on voice cepstral analysis, Benba et al. (IEEE T. Neur. Sys. Reh., vol. 24, pp. 1100-1108, 2016) have reported discrimination between patients with Parkinson's disease and different neurological disorders with high classification accuracy up to 90%. Using the same approach, we were able to experimentally separate two groups of normal healthy(More)