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Genetic variations in the matrix metalloproteinase-1 promoter and risk of susceptibility and/or severity of chronic periodontitis in the Czech population.

• Lydie Izakovicova Holla, Michal Jurajda, Antonín Fassmann, Nela Dvořáková, Vladimír Znojil, Jiří Vácha
• Journal of clinical periodontology
• 2004

OBJECTIVES Matrix metalloproteinase-1 (MMP-1) is a potent enzyme degrading extracellular matrix that was implicated in the pathogenesis of chronic periodontitis. Therefore, the aim of our study was… (More)

Altered dopamine D1 and D2 receptor mRNA expression in mesencephalon from mice exposed to repeated treatments with methamphetamine and cannabinoid CB1 agonist methanandamide.

• Leos Landa, Michal Jurajda, Alexandra Šulcová
• Neuro endocrinology letters
• 2012

OBJECTIVES In our previous studies we found that both acute administration of CB1 receptor agonist methanandamide and repeated methanandamide pre-treatment prior to methamphetamine challenge dose… (More)

Genetic risk factors of cisplatin induced ototoxicity in adult patients.

• T Talach, Jonathan A Rottenberg, +5 authors Ermis Vogazianos
• Neoplasma
• 2016

Ototoxicity is an important adverse effect of using Cisplatin (cis-diamminedichloroplatinum) (CDDP) as a form of chemotherapy. The clinical picture of CDDP induced ototoxicity includes perceptive… (More)

Altered cannabinoid CB1 receptor mRNA expression in mesencephalon from mice exposed to repeated methamphetamine and methanandamide treatments.

• Leos Landa, Michal Jurajda, Alexandra Šulcová
• Neuro endocrinology letters
• 2011

OBJECTIVES Since among others also our previous studies suggested an interaction between the endocannabinoid system and methamphetamine brain mechanisms we focused on possible changes in relative… (More)

Depression and Anxiety after Acute Myocardial Infarction Treated by Primary PCI

• Petr Kala, Nela Hudakova, +6 authors Jan Kanovsky
• PloS one
• 2016

AIMS The main objective of the study was to find out prevalence of depression and anxiety symptoms in the population of patients with AMI with ST-segment elevation (STEMI), treated with primary PCI… (More)

Period3 VNTR polymorphism influences the time-of-day pain onset of acute myocardial infarction with ST elevation.

• Jolana Lipková, Zbyněk Šplíchal, +4 authors Monika Pávková Goldbergová
• Chronobiology international
• 2014

It is well established that the incidence and infarct size in acute myocardial infarction (AMI) is subject to circadian variations. At the molecular level, circadian clocks in distinct cells,… (More)

The Role of Inflammatory Response in Stroke Associated Programmed Cell Death.

• Kamil Ďuriš, Zbyněk Šplíchal, Michal Jurajda
• Current neuropharmacology
• 2018

Stroke represents devastating pathology which is associated with a high morbidity and mortality. Initial damage caused directly by the onset of stroke, primary injury, may be eclipsed by secondary… (More)

Cholinergic Anti-inflammatory Pathway and Stroke.

• Kamil Ďuriš, Jolana Lipková, Michal Jurajda
• Current drug delivery
• 2017

BACKGROUND Stroke is devastating cerebrovascular event which is responsible for 6.7 million deaths each year worldwide. Inflammation plays an important role in the pathophysiology of stroke.… (More)

A newly identified single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene.

• Michal Jurajda, Jan Muzík, Lydie Izakovicova Holla, Jiří Vácha
• Molecular and cellular probes
• 2002

Matrix metalloproteinase-1 (MMP-1) is a member of the matrix metalloproteinase enzyme family that degrades components of the extracellular matrix. Recent studies have demonstrated several polymorphic… (More)

Polymorphism Ncol in tumor necrosis factor B is associated with fasting glycemia and lipid parameters in healthy non-obese caucasian subjects.

• Katerina Kankova, Ivana Márova, E. J. M. Jansen, A. Vašků, Michal Jurajda, Jiří Vácha
• Diabetes & metabolism
• 2002

BACKGROUND The study was designed to investigate the associations among polymorphisms TNF-B Ncol and TNF-alpha -308G/A, plasma TNF-alpha levels and metabolic and anthropometric parameters related to… (More)

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