Michal Horáček

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Sternal dehiscence following cardiac surgery has a multifactorial etiology. Significant risk factors contributing to sternal dehiscence include chronic obstructive pulmonary disease (COPD), obesity, or re-exploration due to bleeding or pericardial tamponade. We have focused on the role of allogeneic blood transfusion as a factor leading to the poor healing(More)
The titanocene-ethene complex [Ti(II)(η(2)-C2H4)(η(5)-C5Me5)2] (1) with simple internal alkynes R(1)C≡CR(2) gives complexes [Ti(II)(η(2)-R(1)C≡CR(2))(η(5)-C5Me5)2] {R(1), R(2): Ph, Ph (3), Ph, Me (4), Me, SiMe3 (5), Ph, SiMe3 (6), t-Bu, SiMe3 (7), and SiMe3, SiMe3 (8). In contrast, alkynes with R(1) = Me and R(2) = t-Bu or i-Pr afford allene complexes(More)
A description of the computer program IEFPlus is given. The program is based on the sodium-potassium double chart for classification of salt-water disturbances presented by Siggaard-Andersen. Input variables of the program are: 1. the concentration of sodium in the plasma, representing the sodium concentration in the Ecf, 2. the relative potassium deficit(More)
Functional group transformations at the group 4 metallocene framework have been demonstrated, which have provided relatively straightforward access to otherwise synthetically challenging derivatives. The pendant nitrile group in Ti and Zr metallocene complexes of the type [(η(5)-C5Me5)(η(5)-C5H4CMe2CH2CN)MCl2] was converted into an intramolecularly bound(More)
AIMS To compare an impact of retransfusion of blood processed in cell-saver (CS) with that of cardiopulmonary bypass (CPB) on blood coagulation in patients undergoing cardiac surgery. METHODS Prospective observational study using thromboelastography (TEG). RESULTS TEG samples from 170 patients were analyzed. Cardiopulmonary bypass was used in 100(More)
Aims. To compare an impact of retransfusion of blood processed in cell-saver (CS) with that of cardiopulmonary bypass (CPB) on blood coagulation in patients undergoing cardiac surgery. Methods. Prospective observational study using thromboelastography (TEG). Results. TEG samples from 170 patients were analyzed. Cardiopulmonary bypass was used in 100(More)
Hydrosilane-B(C6F5)3 adducts were found to activate zirconocene dihalides and generate ternary catalytic systems possessing moderate to high activity in ethylene polymerization to high density polyethylene (HDPE). The activation efficacy of the adducts increased with increasing hydride donor ability and decreased with steric crowding of the particular(More)
A retrospective survey was undertaken of 142 adults who had undergone cardiac surgery with cardiopulmonary bypass. According to the manufacturer's instructions for thromboelastography, patients were identified as showing evidence of fibrinolysis if after coming off bypass the Ly30 index was > or =7.5%. In the 20 fibrinolytic patients, fibrinolysis was(More)
1H NMR studies of reactions of titanocene [Cp*2Ti] (Cp* = η5-C5Me5) and its derivatives [Cp*(η5:η1-C5Me4CH2)TiMe] and [Cp*2Ti(η2-CH2[double bond, length as m-dash]CH2)] with excess dihydrogen at room temperature and pressures lower than 1 bar revealed the formation of dihydride [Cp*2TiH2] (1) and the concurrent liberation of either methane or ethane,(More)