Michaelene Fredenburg

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A method for the identification of human bloodstains using a micro-thin-layer immunoassay (TIA) procedure is presented. The equivalent of approximately 0.01 micro /leter of human blood may be detected using this method with anti-human hemoglobin. Blind studies and stability studies indicate that the method is sufficiently specific and sensitive to be of(More)
A method for the detection of fetal hemoglobin in bloodstains by means of thin-layer immunoassay is described. The equivalent of 0.01 microL of blood containing 0.18 to 0.24 microgram of fetal hemoglobin may be detected by this method. Studies with stains up to two years old and blind studies have shown these methods to be sufficiently sensitive and(More)
Presented is a case history of complete rupture of the posterior tibial tendon and its subsequent surgical repair. Treatment included tendon repair followed by physical therapy and orthotic devices. Nine months after repair the patient was experiencing considerably reduced symptomatology but demonstrated significant posterior tibial muscle weakness and(More)
The use of thin-layer immunoassay (TIA) for the direct detection of opiates in unextracted urine is described. This novel immunoassay is capable of detecting less than 1 ng of opiates, rapidly and inexpensively, without the use of radioactive materials or sophisticated analytical instrumentation. The method was evaluated in a study of 68 post mortem urines(More)
Diabetic foot infections are frequently much worse than the initial clinical appearance would indicate. Altered immune response, peripheral vascular disease, and neuropathy are key factors in the production of infection. Treatment must be based upon careful bacteriologic analysis and individualized antibiotic therapy. Surgical debridement, when indicated,(More)
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