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Structure of BamA, an essential factor in outer membrane protein biogenesis.
Outer membrane protein (OMP) biogenesis is an essential process for maintaining the bacterial cell envelope and involves the β-barrel assembly machinery (BAM) for OMP recognition, folding andExpand
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Transcriptional landscape and essential genes of Neisseria gonorrhoeae
The WHO has recently classified Neisseria gonorrhoeae as a super-bacterium due to the rapid spread of antibiotic resistant derivatives and an overall dramatic increase in infection incidences. GenomeExpand
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Structure and function of the PorB porin from disseminating Neisseria gonorrhoeae.
The outer membrane of Gram-negative bacteria contains a large number of channel-forming proteins, porins, for the uptake of small nutrient molecules. Neisseria gonorrhoeae PorBIA (PorB of serotype A)Expand
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Neutral sphingomyelinase 2 is a key factor for PorB‐dependent invasion of Neisseria gonorrhoeae
Disseminated gonococcal infection (DGI) is a rare but serious complication caused by the spread of Neisseria gonorrhoeae in the human host. Gonococci associated with DGI mainly express the outerExpand
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Pilus Phase Variation Switches Gonococcal Adherence to Invasion by Caveolin-1-Dependent Host Cell Signaling
Many pathogenic bacteria cause local infections but occasionally invade into the blood stream, often with fatal outcome. Very little is known about the mechanism underlying the switch from local toExpand
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  • Open Access