Michael Zellerhoff

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We tested the hypothesis that Flat Detector computed tomography (FD-CT) with intravenous contrast medium would allow the calculation of whole brain cerebral blood volume (CBV) mapping (FD-CBV) and would correlate with multislice Perfusion CT (PCT). Twenty five patients were investigated with FD-CBV and PCT. Correlation of the CBV maps of both techniques was(More)
BACKGROUND AND PURPOSE Color has been shown to facilitate both visual search and recognition tasks. It was our purpose to examine the impact of a color-coding algorithm on the interpretation of 2D-DSA acquisitions by experienced and inexperienced observers. MATERIALS AND METHODS Twenty-six 2D-DSA acquisitions obtained as part of routine clinical care from(More)
BACKGROUND AND PURPOSE Recent advances in flat panel detector angiographic equipment have provided the opportunity to obtain physiologic and anatomic information from angiographic examinations. To exploit this possibility, one must understand the factors that affect the bolus geometry of an intra-arterial injection of contrast medium. It was our purpose to(More)
Tissue perfusion measurement during catheter-guided stroke treatment in the interventional suite is currently not possible. In this work, we present a novel approach that uses a C-arm angiography system capable of computed tomography (CT)-like imaging (C-arm CT) for this purpose. With C-arm CT one reconstructed volume can be obtained every 4-6 s which makes(More)
BACKGROUND AND PURPOSE Cerebral blood volume (CBV) is an important parameter in estimating the viability of brain tissue following an ischemic event. We tested the hypothesis that C-arm CT measurements of CBV would correlate well with those made with perfusion CT (PCT). MATERIALS AND METHODS CBV was measured in 12 canines by using PCT and C-arm CT. Two(More)
BACKGROUND AND PURPOSE CBV is a key parameter in distinguishing penumbra from ischemic core. The purpose of this study was to compare CBV measurements acquired with standard PCT with ones obtained with C-arm CT in a canine stroke model. MATERIALS AND METHODS Under an institutionally approved protocol, unilateral MCA strokes were created in 10 canines.(More)
Tomographic perfusion imaging is a well accepted method for stroke diagnosis that is available with current CT and MRI scanners. A challenging new method, which is currently not available, is perfusion imaging with an interventional C-arm CT that can acquire 4-D images using a C-arm angiography system. This method may help to optimize the workflow during(More)