Michael Yu-Chih Chen

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Caffeine is a commonly used neurostimulant that also produces cerebral vasoconstriction by antagonizing adenosine receptors. Chronic caffeine use results in an adaptation of the vascular adenosine receptor system presumably to compensate for the vasoconstrictive effects of caffeine. We investigated the effects of caffeine on cerebral blood flow (CBF) in(More)
BACKGROUND Metabolic syndrome has been shown to be associated with lower levels of plasma N-terminal pro-B-type natriuretic peptide (Nt-proBNP) in the general population. We sought to elucidate the relationship between Nt-proBNP and components of metabolic syndrome in patients with congestive heart failure (CHF). METHODS Fasting blood samples were(More)
Cardiac myxoma arising from the anterior mitral leaflet is extremely rare. A 47-year-old Taiwanese male was found to have a 5 x 4 x 3 cm myxoma originating from the atrial side of the anterior mitral leaflet using transesophageal echocardiography. The tumor was successfully treated by surgical excision. The resected tumor was a well-defined encapsulated(More)
BACKGROUND The interleukin-6 (IL-6) gene promoter G-174C polymorphism has been associated with insulin resistance, hypertension, and coronary artery disease; however, its relationship with plasma PAI-1 level has not yet been studied. METHODS The G-174C genotypes and plasma PAI-1 antigen and activity were determined in 424 Chinese subjects, 207 with(More)
Even with recent techniques, a significant number of patients with multiple injuries cannot be mobilized at an early stage despite the fixation of all fractures. Conventional mobilization aids are not able to provide the prescribed weight bearing needed in fractures, especially those involving both the lower limbs. Robotics is a current technology aimed at(More)
This paper proposes an efficient method for automatically segmenting vessels from angiogram sequences. The method includes two steps: extracting high-contrast angiograms and segmenting vessels. First, we select high-contrast angiograms automatically using vessel intensity distribution. Based on multiscale Hessian-based filtering, we propose an adaptive(More)
Saphenous vein graft (SVG) failure secondary to degeneration can cause significant problems after coronary artery bypass surgery (CABG). Repeat revascularization by percutaneous coronary intervention can be performed after SVG failure but is often associated with less favourable clinical outcome. Treatment for chronic total occlusion (CTO) of native vessels(More)
Pyomyositis is a pyogenic infection of the skeletal muscles causing myalgia and fever in patients. Hematogenous seeding engendered by persistent bacteremia and septic embolism is usually the underlying cause of the disease. Trauma, intravenous drug use, and immunodeficiency are the main predisposing factors.Obturator internus pyomyositis with sciatica has(More)
In obstructive sleep apnea (OSA), recurrent obstruction of the upper airway leads to intermittent hypoxia (IH) during sleep, which can result in impairment of cardiac function. Although exercise can have beneficial effects against IH-induced cardiac dysfunction, the mechanism remains unclear. This study aimed to investigate the interactions of zinc and(More)