Michael W Jopling

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STUDY OBJECTIVE To examine how premedication with clonidine affects opioid use, hemodynamic effects, hormonal responses, and recovery effects. DESIGN Double blind, placebo-controlled study. SETTING Operating room and surgical intensive care unit of a university medical center. PATIENTS 54 patients undergoing elective coronary artery bypass graft(More)
OBJECTIVES To identify the remifentanil dosing regimen providing safe and optimal anesthetic conditions during coronary artery bypass graft surgery and to evaluate postoperative recovery characteristics. DESIGN Open-label, randomized, parallel group. SETTING Three centers in the United States. PARTICIPANTS Seventy-two patients with left ventricular(More)
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