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MOTIVATION Recent evidence shows significant involvement of microRNAs (miRNAs) in the initiation and progression of numerous cancers; however, the role of these in tumor drug resistance remains unknown. RESULTS By comparing global miRNA and mRNA expression patterns, we examined the role of miRNAs in resistance to the 'pure antiestrogen' fulvestrant, using(More)
  • Nonoy Bandillo, Chitra Raghavan, Pauline Andrea Muyco, Ma Anna Lynn Sevilla, Irish T Lobina, Christine Jade Dilla-Ermita +8 others
  • 2013
This article describes the development of Multi-parent Advanced Generation Inter-Cross populations (MAGIC) in rice and discusses potential applications for mapping quantitative trait loci (QTLs) and for rice varietal development. We have developed 4 multi-parent populations: indica MAGIC (8 indica parents); MAGIC plus (8 indica parents with two additional(More)
  • Santosh Nanda, Michael B. Havert, Gloria M. Calderón, Michael Thomson, Christian Jacobson, Daniel Kastner +1 other
  • 2008
Hepatitis C virus infection leads to a high rate of chronicity. Mechanisms of viral clearance and persistence are still poorly understood. In this study, hepatic gene expression analysis was performed to identify any molecular signature associated with the outcome of hepatitis C virus (HCV) infection in chimpanzees. Acutely HCV-infected chimpanzees with(More)
Intelligence (Wechsler Intelligence Scale for Children R and III, 1992) and written language attainment (BAS Word Reading, Neale Analysis of Reading, Vernon Graded Word Spelling) data for around 250 children attending a specialist school for dyslexics are presented. The Wechsler scales data show some evidence for 'ACID' and 'SCAD' profile effects on the(More)
Information on the effect of stress on the allele-specific expression (ASE) profile of rice hybrids is limited. More so, the association of allelically imbalanced genes to important traits is yet to be understood. Here we assessed allelic imbalance (AI) in the heterozygote state of rice under non- and water-stress treatments and determined association of(More)
Pressure necrosis of the skin is a rarely reported avoidable complication of prone positioning that can be minimised by active collaboration between care teams. We report a case of pressure necrosis of the chin after prone ventilation in the intensive care setting. Such injuries pose a risk of infection, possible need for surgical intervention, and(More)
Improvised explosive devices (IEDs) are a major threat to coalition troops in recent asymmetric conflicts such as Afghanistan. Soldiers still rely heavily on their own senses to detect and assess IED threats, requiring good IED awareness training methods. Three prototype training tools developed for the Canadian Forces are presented here as a "blended"(More)
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