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Polychlorinated biphenyls (pcbs) are compounds that were once used as insulators in electrical transmission lines and in the production of polymers. Each pcb diff ers by the quantity and location of the chlorine atoms. An example of one of the many diff erent pcbs is shown to the right. pcb production was halted in due to their potential toxicity, but… (More)
Dynorphin A (1-17) (dynorphin) acts preferentially and with high affinity at the kappa-opioid receptor, for which it is the natural, endogenous ligand. Interest in designing new ligands to interact at the kappa-opioid receptor is based in part on the desire to circumvent some of the problems associated with mu-opioid ligands such as morphine. The… (More)