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We can recover approximately a sparse signal with limited noise, i.e, a vector of length d with at least d − m zeros or near-zeros, using little more than m log(d) nonadaptive linear measurements rather than the d measurements needed to recover an arbitrary signal of length d. Several research communities are interested in techniques for measuring and(More)
Solitary metastatic brain tumors are the most common intracranial neoplasms encountered by neurosurgeons. Surgical resection of brain metastasis with whole brain radiotherapy (WBR) significantly increases survival in comparison with WBR alone. Stereotactic radiosurgery (SR) seems to provide results that are similar to those of surgical resection. To analyze(More)
The cyclin-dependent kinase (CDK) inhibitor p21WAFI/CIP1is a multido-niain. multifunctional protein and a candidate tumor suppressor. Here, we show that, among rationally designed and tumor-associated mutants of hu man p21 ectopically expressed in U-2-OS cells, those that are selectively deficient in binding to either cyclin or CDK are partially impaired in(More)
We describe an ultrasonic instrument for continuous real-time analysis of the fractional mixture of a binary gas system. The instrument is particularly well suited to measurement of leaks of a high molecular weight gas into a system that is nominally composed of a single gas. Sensitivity < 5 × 10(-5) is demonstrated to leaks of octaflouropropane (C3F8)(More)
Glutathione (GSH) is the most abundant cellular thiol playing an essential role in preserving a reduced cellular environment. Cellular GSH levels can be efficiently reduced by the GSH biosynthesis inhibitor, L-buthionine sulfoximine (BSO). The aim of our study was to determine the role of GSH in the growth of two C-cluster enteroviruses, poliovirus type 1(More)
Lentiviral vectors have proved an effective method to deliver transgenes into the brain; however, they are often hampered by a lack of spread from the site of injection. Modifying the viral envelope with a portion of a rabies envelope glycoprotein can enhance spread in the brain by using long-range axon projections to facilitate retrograde transport. In(More)
The concept of Wave Field Synthesis (WFS) nowadays is a well known audio reproduction method. Based on the Huygens principle numerous secondary sound sources (loudspeakers) are used to create a replica of a primary sources wave fronts. Due to the fact that there is no standardised speaker placement when using WFS the positioning of the secondary sources can(More)
BACKGROUND We compared patterns of medical resource utilization and costs among patients receiving a serotonin-norepinephrine reuptake inhibitor (venlafaxine), one of the selective serotonin reuptake inhibitors (SSRIs), one of the tricyclic agents (TCAs), or 1 of 3 other second-line therapies for depression. METHOD Using claims data from a national(More)
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