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Many approaches to Bayesian image segmentation have used maximum a posteriori (MAP) estimation in conjunction with Markov random fields (MRF). Although this approach performs well, it has a number of disadvantages. In particular, exact MAP estimates cannot be computed, approximate MAP estimates are computationally expensive to compute, and unsupervised(More)
We show that the set SA(G) of equivalence classes of synchronously automatic structures on a geometrically finite hyperbolic group G is dense in the product of the sets SA(P) over all maximal parabolic subgroups P. The set BSA(G) of equivalence classes of biautomatic structures on G is isomorphic to the product of the sets BSA(P) over the cusps (conjugacy(More)
We have performed the first extensive profiling of Epstein-Barr virus (EBV) miRNAs on in vivo derived normal and neoplastic infected tissues. We describe a unique pattern of viral miRNA expression by normal infected cells in vivo expressing restricted viral latency programs (germinal center: Latency II and memory B: Latency I/0). This includes the complete(More)
Classifying kinases based entirely on small molecule selectivity data is a new approach to drug discovery that allows scientists to understand relationships between targets. This approach combines the understanding of small molecules and targets, and thereby assists the researcher in finding new targets for existing molecules or understanding selectivity(More)