Michael Sfakianakis

Learn More
BACKGROUND The effects of azathioprine (AZA) and budesonide (BUD) on mucosal healing and histologic remission of Crohn's disease (CD) are insufficiently studied. In this prospective study we evaluated the comparative effects of AZA and BUD on endoscopic and histologic activity in patients with steroid-dependent Crohn's ileocolitis or proximal colitis who(More)
BACKGROUND The long-term effectiveness of azathioprine, in Crohn's disease (CD) patients remains a matter of debate. This study aims at assessing the effectiveness and safety of azathioprine in patients treated continuously for less or more than 4 years. METHODS Patients with steroid-dependent Crohn's disease in remission on azathioprine (2-2.5 mg/kg) for(More)
GROWTH FACTOR BINDING PROTEIN-5 (IGFBP-5) IS RELATED TO VITAMIN D STATUS IN PATIENTS WITH OSTEOPOROSIS $.E. Scharla, U.G. Lempert, R. Ziegler, T.L. Linkhart, and S. Mohan, Klinik am Kurpark, Schussenrieder Sir.5, 00326 Aulendorf,Germany Insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) are important modulators of bone metabolism. IGFBP-5(More)
GROWTH FACTOR BINDING PROTEIN-5 (IGFBP-5) IS RELATED TO VITAMIN D STATUS IN PATIENTS WITH OSTEOPOROSIS $.E. Scharla, U.G. Lempert, R. Ziegler, T.L. Linkhart, and S. Mohan, Klinik am Kurpark, Schussenrieder Sir.5, 00326 Aulendorf,Germany Insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) are important modulators of bone metabolism. IGFBP-5(More)
BACKGROUND & AIMS To compare the efficacy of controlled-release budesonide capsules with that of mesalamine for maintaining remission and improving quality of life (QOL) in patients with steroid-dependent Crohn's disease. METHODS Fifty-seven patients (25 men; mean age, 32 +/- 10.1 yr) with quiescent steroid-dependent Crohn's ileitis, ileocolitis, or(More)
OBJECTIVE:The aim of this prospective study was to assess whether the coadministration of azathioprine (AZA) and olsalazine is superior to AZA monotherapy in maintaining remission of steroid-dependent ulcerative colitis (UC).METHODS:Patients with steroid-dependent UC in remission were randomized to receive AZA alone (2.2 mg/kg) or in combination with(More)
  • 1