Werner Poewe20
Klaus Seppi13
Christoph Scherfler12
20Werner Poewe
13Klaus Seppi
12Christoph Scherfler
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A better understanding of learning processes in arithmetic in healthy adults can guide research into learning disabilities such as dyscalculia. The goal of the present functional magnetic resonance imaging study was to investigate the ongoing process of learning itself. No training was provided prior to the scanning session. Training consisted in a higher(More)
Activation time (AT) imaging from electrocardiographic (ECG) mapping data has been developing for several years. By coupling ECG mapping and three-dimensional (3-D) + time anatomical data, the electrical excitation sequence can be imaged completely noninvasively in the human heart. In this paper, a bidomain theory-based surface heart model AT imaging(More)
Recent imaging studies could show that fact acquisition in arithmetic is associated with decreasing activation in several frontal and parietal areas, and relatively increasing activation within the angular gyrus, indicating a switch from direct calculation to retrieval of a learned fact from memory. So far, however, little is known about the transfer of(More)
This functional magnetic resonance imaging (fMRI) study systematically investigates whether there is a neurofunctional overlap of nonsymbolic numerical and spatial cognition in (intra)parietal regions in children and adults. The study also explores the association between finger use and (nonsymbolic) number processing across development. Twenty-four healthy(More)
BACKGROUND Functional magnetic resonance imaging (fMRI) studies investigating the neural mechanisms underlying developmental dyscalculia are scarce and results are thus far inconclusive. Main aim of the present study is to investigate the neural correlates of nonsymbolic number magnitude processing in children with and without dyscalculia. METHODS 18(More)
Medial temporal lobe (MTL) areas are well known to serve episodic memory functions; their contribution to semantic memory has been occasionally noticed but not studied in detail. In the present fMRI study, 35 right-handed and 35 left-handed healthy subjects performed a semantic decision paradigm during which subjects heard spoken concrete nouns designating(More)
  • Bettina Kuenz, Andreas Lutterotti, Rainer Ehling, Claudia Gneiss, Monika Haemmerle, Carolyn Rainer +4 others
  • 2008
BACKGROUND There is accumulating evidence from immunological, pathological and therapeutic studies that B cells are key components in the pathophysiology of multiple sclerosis (MS). METHODOLOGY/PRINCIPAL FINDINGS In this prospective study we have for the first time investigated the differences in the inflammatory response between relapsing and progressive(More)
OBJECTIVE We applied diffusion-tensor imaging (DTI) including measurements of mean diffusivity (MD), a parameter of brain tissue integrity, fractional anisotropy (FA), a parameter of neuronal fiber integrity, as well as voxel-based morphometry (VBM), a measure of gray and white matter volume, to detect brain tissue changes in patients with idiopathic rapid(More)
BACKGROUND Patients with alcohol addiction show a number of transient or persistent neurological and psychiatric deficits. The complexity of these brain alterations suggests that several brain areas are involved, although the definition of the brain alteration patterns is not yet accomplished. AIM To determine brain atrophy patterns in patients with(More)
Little is known about how adults process fractions and how fractions are represented in the brain. The intraparietal sulcus is assumed to host an analogue representation of number magnitude. It is unknown, however, how the magnitude of fractions is represented in the brain. Fraction magnitude might be represented by the numerical value of the fraction as a(More)