Michael Schlosser

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The location of brain regions essential for auditory language comprehension is an important consideration in the planning of neurosurgical procedures that involve resections within the dominant temporal lobe. Language testing during intraoperative and extraoperative cortical stimulation has been the primary method for localizing these regions; however,(More)
Islet autoantibodies are important in diabetes classification and risk assessment, and as endpoints in observational studies. The Diabetes Autoantibody Standardization Program (DASP) aims to improve and standardise measurement of autoantibodies associated with type 1 diabetes. We report results for glutamic acid decarboxylase autoantibodies (GADA) and islet(More)
A phylogenetic survey using the polymerase chain reaction (PCR) has identified four major P element subfamilies in the saltans and willistoni species groups of Drosophila. One subfamily, containing about half of the sequences studied, consists of elements that are very similar to the canonical (and active) P element from D. melanogaster. Within this(More)
Amide proton transfer (APT) imaging is a technique in which the nuclear magnetization of water-exchangeable amide protons of endogenous mobile proteins and peptides in tissue is saturated, resulting in a signal intensity decrease of the free water. In this work, the first human APT data were acquired from 10 patients with brain tumors on a 3T whole-body(More)
Aims/hypothesis. The Karlsburg Type I (insulin-dependent) diabetes risk study on schoolchildren aims to evaluate the predictive diagnostic value of diabetes-associated autoantibodies in the general population. Methods. We took capillary serum from 9419 schoolchildren, aged 6–17 years, for testing of autoantibodies (AAbs) to glutamic acid decarboxylase(More)
Type 1 diabetes (T1D) is an autoimmune disease linked with genetic factors as well as with environmental triggers, such as virus infections, but the aetiology is still unclear. The authors analysed serum from autoantibody-positive (n=50) and autoantibody-negative (n=50) schoolchildren as well as children newly diagnosed with T1D (n=47; time from diagnosis,(More)
Most decision tree algorithms focus on uni variate i e axis parallel tests at each inter nal node of a tree Oblique decision trees use multivariate linear tests at each non leaf node This paper reports a novel approach to the construction of non linear decision trees The crux of this method consists of the gen eration of new features and the augmenta tion(More)
Abstract. After reviewing some fundamental facts from the theory of theta hypergeometric series we derive, using indefinite summation, several summation, transformation, and expansion formulas for multibasic theta hypergeometric series. Some of the identities presented here generalize corresponding formulas given in Chapter 11 of the Gasper and Rahman book(More)
OBJECT Functional magnetic resonance (fMR) imaging of the motor cortex is a potentially powerful tool in the preoperative planning of surgical procedures in and around the rolandic region. Little is known about the patterns of fMR imaging activation associated with various pathological lesions in that region or their relation to motor skills before surgical(More)