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FL and a paper entitled " Use of the "Logical Analysis of Data" Method for Assessing Long-Term Mortality Risk After Exercise Electrocardiography " was submitted for publication to a medical journal. Abstract The objective of this study was to distinguish within a population of patients with known or suspected coronary artery disease groups at high and at(More)
An ambulatory medical record system was implemented as a pilot project to determine the clinical and operational impacts of using interactive, computer-based systems in the outpatient setting. Of the 58 physicians who attempted to use the AMR system, 28 continue as active users. Physicians who discontinued use of the system reported a variety of reasons for(More)
OBJECTIVES The purpose of this study was to externally validate the prognostic value of age- and gender-based nomograms and categorical definitions of impaired exercise capacity (EC). BACKGROUND Exercise capacity predicts death, but its use in routine clinical practice is hampered by its close correlation with age and gender. METHODS For a median of 5(More)
The increasing availability of personal genomic tests has led to discussions about the validity and utility of such tests and the balance of benefits and harms. A multidisciplinary workshop was convened by the National Institutes of Health and the Centers for Disease Control and Prevention to review the scientific foundation for using personal genomics in(More)
  • Gregory Pattakos, Colleen G Koch, Mariano E Brizzio, Lillian H Batizy, Joseph F Sabik, Eugene H Blackstone +1 other
  • 2012
BACKGROUND Jehovah's Witness patients (Witnesses) who undergo cardiac surgery provide a unique natural experiment in severe blood conservation because anemia, transfusion, erythropoietin, and antifibrinolytics have attendant risks. Our objective was to compare morbidity and long-term survival of Witnesses undergoing cardiac surgery with a similarly matched(More)
has served on the speakers' bureaus for GlaxoSmithKline and Novartis. Investigators. Short-term clinical effects of tolvaptan, an oral vasopressin antagonist , in patients hospitalized for heart failure: the EVEREST clinical status trials. JAMA. Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled(More)
BACKGROUND Logical Analysis of Data is a methodology of mathematical optimization on the basis of the systematic identification of patterns or "syndromes." In this study, we used Logical Analysis of Data for risk stratification and compared it to regression techniques. METHODS AND RESULTS Using a cohort of 9454 patients referred for exercise testing,(More)
BACKGROUND Currently, the only function of the resting electrocardiogram (ECG) in patients referred for exercise testing is to determine whether imaging is mandated. It is unknown if subtle ECG findings in those patients with clinically normal resting ECGs have prognostic significance. METHODS We performed a single-center cohort study of 18,964 patients(More)
Many modern physician specialists like to think of their work as grounded in strong science. Yet 5 years ago, a group of cardiol-ogists published their findings on the science underlying over 2700 practice recommendations issued by their specialty societies. 1 Only 314 (or 11%) were based on 'level A' evidence, that is, evidence based on multiple well-done(More)