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BACKGROUND Molecular interaction Information is a key resource in modern biomedical research. Publicly available data have previously been provided in a broad array of diverse formats, making access to this very difficult. The publication and wide implementation of the Human Proteome Organisation Proteomics Standards Initiative Molecular Interactions (HUPO(More)
A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the(More)
This diary study examined daily fluctuation in marital lust over a 56-day period. The purposes of the study were to describe typical patterns of lust over time and to examine intrapersonal and interpersonal associations between relationship affect, relationship states, and marital lust. We also tested various daily moderational predictions. Four patterns of(More)
We have developed two models, the stability model and the profile model, to identify non-synonymous single base changes (the most common cause of monogenic disease) that have deleterious effects on protein function in vivo. The stability model analyzes the effect of the resulting amino acid change on protein stability by utilizing structural information(More)
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