Learn More
PURPOSE In this article, the authors present a tutorial on the use of developmental trajectories for studying language and cognitive impairments in developmental disorders and compare this method with the use of matching. METHOD The authors assess the strengths, limitations, and practical implications of each method. The contrast between the methodologies(More)
Contemporary models of the neural system that supports reading propose that activity in a ventral occipitotemporal area (vOT) drives activity in higher-order language areas, for example, those in the posterior superior temporal sulcus (pSTS) and anterior superior temporal sulcus (aSTS). We used fMRI with dynamic causal modeling (DCM) to investigate evidence(More)
We measured 1 changes in intelligence quotient (IQ) between time 1 and time 2 in teenage subjects and searched their brains for regions where changes in IQ predicted changes in grey matter density (GMD). We found highly significant effects in two localized brain regions, after correcting for multiple comparisons across the whole brain. This provided an(More)
We report a cross-syndrome comparison of the development of holistic processing in face recognition in school-aged children with developmental disorders: autism, Down syndrome, and Williams syndrome. The autism group was split into two groups: one with high-functioning children and one with low-functioning children. The latter group has rarely been studied(More)
An increasing number of connectionist models have been proposed to explain behavioural deficits in developmental disorders. These simulations motivate serious consideration of the theoretical implications of the claim that a developmental disorder fits within the parameter space of a particular computational model. We examine these issues in depth with(More)
Our objective was to demonstrate that human population-level, right-handedness, is not species specific, precipitated from language areas in the brain, but rather is context specific and inherited from a behavior common to both humans and great apes. In general, previous methods of assessing human handedness have neglected to consider the context of action,(More)
Below is the unedited précis of a book that is being accorded BBS multiple book review. This preprint has been prepared for potential commentators who wish to nominate themselves for formal commentary invitation. Please do not write a commentary unless you receive a formal invitation. Invited commentators will receive full instructions. Commentary must be(More)
Williams Syndrome (WS) is marked by a relative strength in verbal cognition coupled with a serious impairment in non-verbal cognition. A strong deficit in numerical cognition has been anecdotally reported in this disorder; however, its nature has not been systematically investigated. Here, we tested 14 children with WS (mean age=7 years 2 months), 14(More)
Is a dog ever too old to learn new tricks? We review recent findings on sensitive periods in brain development, ranging from sensory processing to high-level cognitive abilities in humans. We conclude that there are multiple varieties of, and mechanisms underlying, these changes. However, many sensitive periods may be a consequence of the basic processes(More)