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PURPOSE In this article, the authors present a tutorial on the use of developmental trajectories for studying language and cognitive impairments in developmental disorders and compare this method with the use of matching. METHOD The authors assess the strengths, limitations, and practical implications of each method. The contrast between the methodologies(More)
Contemporary models of the neural system that supports reading propose that activity in a ventral occipitotemporal area (vOT) drives activity in higher-order language areas, for example, those in the posterior superior temporal sulcus (pSTS) and anterior superior temporal sulcus (aSTS). We used fMRI with dynamic causal modeling (DCM) to investigate evidence(More)
We measured 1 changes in intelligence quotient (IQ) between time 1 and time 2 in teenage subjects and searched their brains for regions where changes in IQ predicted changes in grey matter density (GMD). We found highly significant effects in two localized brain regions, after correcting for multiple comparisons across the whole brain. This provided an(More)
We report a cross-syndrome comparison of the development of holistic processing in face recognition in school-aged children with developmental disorders: autism, Down syndrome, and Williams syndrome. The autism group was split into two groups: one with high-functioning children and one with low-functioning children. The latter group has rarely been studied(More)
An increasing number of connectionist models have been proposed to explain behavioural deficits in developmental disorders. These simulations motivate serious consideration of the theoretical implications of the claim that a developmental disorder fits within the parameter space of a particular computational model. We examine these issues in depth with(More)
Recent findings suggest that children with autism may be impaired in the perception of biological motion from moving point-light displays. Some children with autism also have abnormally high motion coherence thresholds. In the current study we tested a group of children with autism and a group of typically developing children aged 5 to 12 years of age on(More)
Our objective was to demonstrate that human population-level, right-handedness, is not species specific, precipitated from language areas in the brain, but rather is context specific and inherited from a behavior common to both humans and great apes. In general, previous methods of assessing human handedness have neglected to consider the context of action,(More)
We present a connectionist model of a general system for producing inflected words. The Multiple Inflection Generator (MIG) combines elements of several previous models (e.g., association between phonological representations of stem and inflection form: Rumelhart & McClelland, 1986; multiple inflections for a grammatical class: Hoeffner & McClelland, 1993;(More)
Socioeconomic status (SES) is an important environmental predictor of language and cognitive development, but the causal pathways by which it operates are unclear. We used a computational model of development to explore the adequacy of manipulations of environmental information to simulate SES effects in English past-tense acquisition, in a data set(More)