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— An adaptive transversal equalizer based on the least-mean-square (LMS) algorithm, operating in an environment with a temporally correlated interference, can exhibit better steady-state mean-square-error (MSE) performance than the corresponding Wiener filter. This phenomenon is a result of the nonlinear nature of the LMS algorithm and is obscured by(More)
The purpose of this study was to determine to what extent high-resolution computed tomography (HRCT) of the lungs can distinguish active inflammatory disease from inactive cicatricial disease in patients treated for Wegener's granulomatosis (WG). Twenty-eight WG patients with active pulmonary disease underwent a first HRCT examination immediately before(More)
OBJECTIVES To assess the prevalence, clinical characteristics, and treatment options of patients with interstitial lung disease (ILD) in polymyositis and dermatomyositis (PM/DM). PATIENTS AND METHODS Sixty-three consecutive patients with PM/DM underwent standardized screening. Patients with ILD were monitored prospectively, and graded immunosuppression(More)
The Gram-positive bacterium Staphylococcus aureus, similar to other pathogens, binds human complement regulators Factor H and Factor H related protein 1 (FHR-1) from human serum. Here we identify the secreted protein Sbi (Staphylococcus aureus binder of IgG) as a ligand that interacts with Factor H by a-to our knowledge-new type of interaction. Factor H(More)
PURPOSE To evaluate the diagnostic accuracy of common magnetic resonance (MR) imaging sequences for detection of small pulmonary nodules by using a chest phantom and porcine lungs containing simulated lesions. MATERIALS AND METHODS Fourteen porcine lungs containing 366 porcine myocardial tissue implants were inflated inside a phantom. Two-dimensional (2D)(More)
A low probability of intercept (LPI), or low probability of detection (LPD) communication technique known as cyclic code shift keying (CCSK) is described. We discuss the basic concepts of CCSK and describe a system based on the use of random or pseudorandom codes for biphase modulation. We use simulation to show that the bit error rate (BER) for CCSK can be(More)
Upon host infection, the human pathogenic microbe Staphylococcus aureus (S. aureus) immediately faces innate immune reactions such as the activated complement system. Here, a novel innate immune evasion strategy of S. aureus is described. The staphylococcal proteins surface immunoglobulin-binding protein (Sbi) and extracellular fibrinogen-binding protein(More)
Group A streptococci (GAS) utilize soluble human complement regulators to evade host complement attack. Here, we characterized the binding of the terminal complement complex inhibitor complement Factor H-related protein 1 (CFHR1) and of the C3 convertase regulator Factor H to the streptococcal collagen-like proteins (Scl). CFHR1 and Factor H, but no other(More)
—We present an approximate analysis approach to the computation of probability of error and mean burst error length for a decision feedback equalizer (DFE) that takes into account feedback of decision errors. The method uses a reduced-state Markov model of the feedback process and is applicable to linear modulation formats. We use this technique to analyze(More)
PURPOSE To use porcine lung explants for reconstructing possible situations in which a vessel wall disruption might have occurred in a patient suffering fatal hemoptysis after pulmonary embolectomy with a hydrodynamic thrombectomy device. METHODS A 76-year-old woman with massive pulmonary embolism underwent transvenous pulmonary embolectomy using a 6-F(More)