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Alphaxalone-alphadolone (Althesin), diluted and administered as a controlled infusion, was used as a sedative for 30 patients in an intensive therapy unit. This technique allowed rapid and accurate control of the level of sedation. It had three particularly useful applications: it provided "light sleep," allowed rapid variation in the level of sedation, and(More)
The adaptation of black and polar bears to their environments is proportional to the severity of climate and food restriction. Both black and polar bears mate during the spring, despite differences in their recent metabolic state. Reproductive activity in black bears follows 4 mo of torpor, whereas reproduction in polar bears occurs prior to torpor. The(More)
Contamination of the Arctic ecosystem by anthropogenic compounds has resulted in exposure of polar bear (Ursus maritimus) to lipophilic chlorinated hydrocarbon contaminants (CHCs) accumulated through the marine food web. Liver samples were collected from 16 adult male polar bears in the Canadian arctic and subjected to chemical analysis for CHCs and(More)
DEXMEDETOMIDINE is a highly selective ␣ 2 adrenocep-tor agonist that has sedative and analgesic properties with associated reduction in opioid and anesthetic requirements. 1–11 One significant advantage of dexme-detomidine is that in the clinical dose range there is no respiratory depression. 12–14 The agonistic action on the ␣ 2 adrenoceptors in the(More)
Nuss described a minimally invasive technique for correcting pectus excavatum in children. A curved stainless-steel bar is inserted behind the sternum through the chest cavity with the convex surface face down, then rotated 180 degrees to elevate the sternum and correct the deformity. The procedure gained wide acceptance in children. The purpose of this(More)
OBJECTIVE We undertook this study to understand the factors at our transplant center that contribute to patients' return to the ICU after their liver transplant and their initial discharge from that unit. Patients who, after liver transplantation, fail discharge from the Intensive Care Unit (ICU) and must be readmitted to that unit may well utilize many(More)
BACKGROUND Liver transplantation for unresectable hepatocellular carcinoma yields disappointing results. Most cases recur within 2 years, often in the transplanted liver. METHODS A combination of neoadjuvant doxorubicin and orthotopic liver transplantation was used in 20 patients with unresectable hepatocellular carcinoma confined to the liver. Seventeen(More)
BACKGROUND Several technical solutions have been proposed for patients with situs inversus (SI) needing liver transplantation. This report describes the hepatic replacement in a patient with complete SI with dextrocardia. In the only other reported patient with complete SI the donor right lobe was placed over the vertebral column and the stomach to align(More)