Michael Rabinoff

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Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). Specific dopamine related gene alleles have previously been found to be associated with smoking initiation, maintenance and cessation. We investigated the association between specific dopamine related gene alleles and both change in smoking behavior and lung(More)
We investigated tobacco industry documents and other sources for evidence of possible pharmacological and chemical effects of tobacco additives. Our findings indicated that more than 100 of 599 documented cigarette additives have pharmacological actions that camouflage the odor of environmental tobacco smoke emitted from cigarettes, enhance or maintain(More)
The study objective was to evaluate the usefulness of Classification and Regression Trees (CART), to classify clinical responders to antidepressant and placebo treatment, utilizing symptom severity and quantitative EEG (QEEG) data. Patients included 51 adults with unipolar depression who completed treatment trials using either fluoxetine, venlafaxine or(More)
Objective: To determine if treatment with S-adenosylmethionine (SAMe) might lead to cognitive and behavioral improvement in patients with Alzheimer's disease (AD). Interventions: We conducted a prospective, open-label study of six subjects who were given oral SAMe over 12 weeks and measured the effects on cognition and behavior. Outcome measures: Outcome(More)
To the Editor: Tuomainen et al 1 have noted an association between increased iron stores, as measured by a reduced ratio of serum transferrin receptor concentration to serum ferritin concentration, and excess risk of acute myocardial infarction (AMI). It has been suggested that iron can catalyze toxic redox reactions, which may lead to an increased risk for(More)
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